Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438225 | 0.87 | MCHR1 (0.42) | NOS3NOS1NOS2MCHR1NR4A2 | |
| SCHEMBL440069 | 0.82 | NOS2 (0.41) | NOS3NOS1NOS2MCHR1ASIC3 | |
| SCHEMBL439825 | 0.81 | NR4A2 (0.60) | NOS3NOS1NOS2MCHR1NR4A2 | |
| SCHEMBL439579 | 0.78 | NR4A2 (0.65) | NR4A2PPARANPSR1RXFP1PDPK1 | |
| SCHEMBL438834 | 0.78 | NOS2 (0.50) | NOS3NOS1NOS2MCHR1NR4A2 | |
| SCHEMBL436991 | 0.77 | NOS3 (0.41) | NOS3NOS1NOS2MCHR1NR4A2 | |
| SCHEMBL439849 | 0.77 | POLB (0.43) | NOS3NOS1NOS2MCHR1ASIC3 | |
| SCHEMBL439708 | 0.76 | MCHR1 (0.43) | NOS3NOS1NOS2MCHR1NR4A2 | |
| SCHEMBL436015 | 0.75 | NOS3 (0.39) | NOS3NOS1NOS2MCHR1ASIC3 | |
| SCHEMBL438887 | 0.75 | MCHR1 (0.44) | NOS3NOS1NOS2MCHR1ASIC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |