SCHEMBL43971

SCHEMBL43971

COC(=O)C1CCNC1=O

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
ALDH1A1 P00352 1/20 0.38
MAP2K1 Q02750 2/20 0.37
HSD17B10 Q99714 1/20 0.37
CCR2 P41597 1/20 0.37
ATM Q13315 1/20 0.36
ACACB O00763 1/20 0.36
CYP1A2 P05177 1/20 0.36
HIF1A Q16665 1/20 0.36
POLB P06746 1/20 0.35
PPM1B O75688 1/20 0.35
PTPN1 P18031 1/20 0.35
PPP1CC P36873 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21662208 1.00 L3MBTL1 (0.41) L3MBTL1ALDH1A1MAP2K1HSD17B10CCR2
SCHEMBL2789189 0.89 L3MBTL1 (0.54) L3MBTL1ALDH1A1HSD17B10CCR2ATM
SCHEMBL14169786 0.87 L3MBTL1 (0.49) L3MBTL1ALDH1A1HSD17B10CCR2ATM
SCHEMBL11487920 0.81 CYP1A2 (0.34) CYP1A2HIF1A
SCHEMBL9038834 0.79 MAPK1 (0.38) L3MBTL1ALDH1A1HSD17B10CCR2ACACB
SCHEMBL907623 0.79 MAPT (0.45) ALDH1A1HSD17B10ACACBPOLBPPM1B
SCHEMBL7542627 0.79 MAPK1 (0.38) L3MBTL1ALDH1A1HSD17B10CCR2ACACB
SCHEMBL27405623 0.79 MAPT (0.45) ALDH1A1HSD17B10ACACBPOLBPPM1B
SCHEMBL11674331 0.77
SCHEMBL2018377 0.76 L3MBTL1 (0.46) L3MBTL1ALDH1A1HSD17B10CCR2ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129094-A1 NEW QUINOLINE DERIVATIVES ELANCO ANIMAL HEALTH GMBH (DE) 2025-04-24 US claimed
US-12071516-B2 Polymeric stabilizing formulations NANO PRECISION MEDICAL, INC. (US) 2024-08-27 US claimed
EP-4399209-A1 NEW QUINOLINE DERIVATIVES Elanco Animal Health GmbH (DE) 2024-07-17 EP claimed
CN-117957223-A Quinoline derivatives 礼蓝动物保健有限公司 2024-04-30 CN claimed
WO-2023036821-A1 NEW QUINOLINE DERIVATIVES BAYER ANIMAL HEALTH GMBH (DE) 2023-03-16 WO claimed
EP-4148052-A1 NEW QUINOLINE DERIVATIVES Bayer Animal Health GmbH (DE) 2023-03-15 EP claimed
US-20210246271-A1 POLYMERIC STABILIZING FORMULATIONS NANO PRECISION MEDICAL, INC. (US) 2021-08-12 US claimed
US-11021576-B2 Polymeric stabilizing formulations NANO PRECISION MEDICAL, INC. (US) 2021-06-01 US claimed
US-20200040140-A1 POLYMERIC STABILIZING FORMULATIONS NANO PRECISION MEDICAL, INC. (US) 2020-02-06 US claimed
US-10479868-B2 Polymeric stabilizing formulations NANO PRECISION MEDICAL, INC. (US) 2019-11-19 US claimed
US-20170274089-A1 POLYMERIC STABILIZING FORMULATIONS NANO PRECISION MEDICAL, INC. 2017-09-28 US claimed
EP-2604289-B1 RADIAL SHAPE OF POLYMER COMPOUND CONTAINING IODINE, PREPARATION METHOD THEREOF, AND CT CONTRAST MEDIUM COMPOSITION CONTAINING SAME KOREA RES INST BIOSCIENCE & BIOTECHNOLOGY (KR) 2017-08-16 EP claimed
US-9387267-B2 Iodine-containing radial-shaped macromolecular compounds, preparation method thereof and contrast media compositions for CT comprising the same KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2016-07-12 US claimed
WO-2016037128-A1 POLYMERIC STABILIZING FORMULATIONS NANO PRECISION MEDICAL, INC. (US) 2016-03-10 WO claimed
CN-105085930-A Novel dendritic macromolecule and its preparation method and use HAN BING 2015-11-25 CN claimed
CN-104558625-A Novel dendrimer as well as preparation and application thereof HAN BING 2015-04-29 CN claimed
CN-104558627-A Novel dendrimer as well as preparation and application thereof HAN BING 2015-04-29 CN claimed
CN-103282056-A Iodine-containing radial macromolecular compound, preparation method thereof and CT contrast medium composition containing same KOREA RES INST OF BIOSCIENCE 2013-09-04 CN claimed
EP-2604289-A2 RADIAL SHAPE OF POLYMER COMPOUND CONTAINING IODINE, PREPARATION METHOD THEREOF, AND CT CONTRAST MEDIUM COMPOSITION CONTAINING SAME Korea Research Institute of Bioscience and Biotechnology (KR) 2013-06-19 EP claimed
US-20130150529-A1 IODINE-CONTAINING RADIAL-SHAPED MACROMOLECULAR COMPOUNDS, PREPARATION METHOD THEREOF AND CONTRAST MEDIA COMPOSITIONS FOR CT COMPRISING THE SOME KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2013-06-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170274089-A1 POLYMERIC STABILIZING FORMULATIONS IAPP, INSR, GPR119 L3MBTL1 4640/4885ALDH1A1 2610/4885MAP2K1 4588/4885
US-11021576-B2 Polymeric stabilizing formulations IAPP, INSR, GPR119 L3MBTL1 4640/4885ALDH1A1 2610/4885MAP2K1 4588/4885
US-20130150529-A1 IODINE-CONTAINING RADIAL-SHAPED MACROMOLECULAR COMPOUNDS, PREPARATION METHOD THEREOF AND CONTRAST MEDIA COMPOSITIONS FOR CT COMPRISING THE SOME IGFBP1, IGFBP5, IGFBP2 L3MBTL1 4845/4885ALDH1A1 4766/4885MAP2K1 913/4885
US-12071516-B2 Polymeric stabilizing formulations VEGFA, CD44, CFTR L3MBTL1 2388/4885ALDH1A1 3181/4885MAP2K1 4769/4885
US-10479868-B2 Polymeric stabilizing formulations IAPP, INSR, GPR119 L3MBTL1 4640/4885ALDH1A1 2610/4885MAP2K1 4588/4885
US-20250129094-A1 NEW QUINOLINE DERIVATIVES RECQL, QTRT2, NQO2 L3MBTL1 2122/4885ALDH1A1 1516/4885MAP2K1 4433/4885
US-20200040140-A1 POLYMERIC STABILIZING FORMULATIONS IAPP, INSR, GPR119 L3MBTL1 4640/4885ALDH1A1 2610/4885MAP2K1 4588/4885
US-20210246271-A1 POLYMERIC STABILIZING FORMULATIONS VEGFA, CD44, CFTR L3MBTL1 2388/4885ALDH1A1 3181/4885MAP2K1 4769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.