Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12103678 | 0.81 | ITGB3 (0.42) | AVPR2AVPR1AITGB3ITGA2BTLR7 | |
| SCHEMBL4400842 | 0.80 | NNMT (0.49) | AVPR2AVPR1AITGB3ITGA2BCHEK2 | |
| Hydrochloric Acid SCHEMBL1295961 | 0.80 | DHODH (0.44) | AVPR2AVPR1AITGB3ITGA2BITGAV | |
| Hydrochloric Acid SCHEMBL1295292 | 0.80 | ITGB3 (0.41) | AVPR2AVPR1AITGB3ITGA2BTLR7 | |
| SCHEMBL1295825 | 0.78 | GABRA5 (0.43) | AVPR2AVPR1AITGB3ITGA2BITGAV | |
| Hydrochloric Acid SCHEMBL1296024 | 0.73 | ITGB3 (0.41) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL1295857 | 0.72 | ITGB3 (0.38) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL1295860 | 0.72 | ITGB3 (0.38) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL4403130 | 0.71 | GABRA5 (0.48) | ITGB3ITGA2B | |
| SCHEMBL3426935 | 0.70 | ITGB3 (0.43) | AVPR2AVPR1AITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321308-B9 | PIPERIDINE GPCR AGONISTS | PROSIDION LTD (GB) | 2012-08-08 | — | — | EP | disclosed |
| EP-2321308-B1 | PIPERIDINE GPCR AGONISTS | PROSIDION LTD (GB) | 2012-05-09 | — | — | EP | disclosed |