Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 12/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4400842 | 0.86 | NNMT (0.49) | ITGB3ITGA2BAVPR2AVPR1A | |
| Hydrochloric Acid SCHEMBL1295961 | 0.86 | DHODH (0.44) | ITGB3ITGA2BAVPR2AVPR1AITGAV | |
| SCHEMBL1296046 | 0.81 | GPR119 (0.52) | KDM4E | |
| Hydrochloric Acid SCHEMBL1296024 | 0.79 | ITGB3 (0.41) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL1295102 | 0.79 | GPR119 (0.47) | GABRA5CHRM2MAOABCHEACHE | |
| SCHEMBL1295860 | 0.78 | ITGB3 (0.38) | ITGB3ITGA2BNPC1RAB9AITGAV | |
| SCHEMBL1295857 | 0.78 | ITGB3 (0.38) | ITGB3ITGA2BNPC1RAB9AITGAV | |
| SCHEMBL4400810 | 0.78 | AVPR2 (0.41) | ITGB3ITGA2BAVPR2AVPR1AITGAV | |
| SCHEMBL4403130 | 0.77 | GABRA5 (0.48) | GABRA5ITGB3ITGA2BRAB9APLAT | |
| SCHEMBL12103678 | 0.76 | ITGB3 (0.42) | ITGB3ITGA2BAVPR2AVPR1AITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269734-A1 | PIPERIDINYL GPCR AGONISTS | PROSIDION LIMITED (GB) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269734-A1 | PIPERIDINYL GPCR AGONISTS | GPR119, GPR27, GLP1R | GABRA5 245/4885ITGB3 3442/4885ITGA2B 3353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.