Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1295961 | 0.88 | DHODH (0.44) | ITGB3ITGA2BAVPR2AVPR1ADHODH | |
| SCHEMBL1295825 | 0.86 | GABRA5 (0.43) | ITGB3ITGA2BAVPR2AVPR1A | |
| Hydrochloric Acid SCHEMBL1296024 | 0.81 | ITGB3 (0.41) | ITGB3ITGA2B | |
| SCHEMBL1295860 | 0.80 | ITGB3 (0.38) | ITGB3ITGA2B | |
| SCHEMBL1295857 | 0.80 | ITGB3 (0.38) | ITGB3ITGA2B | |
| SCHEMBL4400810 | 0.80 | AVPR2 (0.41) | ITGB3ITGA2BCHEK2AVPR2AVPR1A | |
| SCHEMBL4403130 | 0.79 | GABRA5 (0.48) | ITGB3ITGA2B | |
| SCHEMBL1296418 | 0.78 | GPR119 (0.48) | NNMT | |
| SCHEMBL12103678 | 0.78 | ITGB3 (0.42) | ITGB3ITGA2BAVPR2AVPR1A | |
| SCHEMBL12106765 | 0.78 | ITGB3 (0.49) | ITGB3ITGA2BCHEK2DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321308-B9 | PIPERIDINE GPCR AGONISTS | PROSIDION LTD (GB) | 2012-08-08 | — | — | EP | disclosed |
| EP-2321308-B1 | PIPERIDINE GPCR AGONISTS | PROSIDION LTD (GB) | 2012-05-09 | — | — | EP | disclosed |