Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27884072 | 0.79 | AGER (0.54) | KMT2AL3MBTL1 | |
| SCHEMBL5713017 | 0.77 | L3MBTL1 (0.40) | KMT2AALDH1A1L3MBTL1FKBP1AATM | |
| SCHEMBL13900757 | 0.77 | ALDH1A1 (0.53) | LMNAHTTMAPTNPSR1HPGD | |
| SCHEMBL4193440 | 0.76 | CA12 (0.47) | LMNAHPGDRAB9ASMN1; SMN2CA12 | |
| SCHEMBL10207431 | 0.76 | HSD11B1 (0.56) | KMT2AL3MBTL1 | |
| SCHEMBL4246502 | 0.75 | CA12 (0.46) | LMNAHPGDRAB9ASMN1; SMN2CA12 | |
| SCHEMBL9257531 | 0.73 | ALDH1A1 (0.59) | LMNAHTTMAPTNPSR1HPGD | |
| SCHEMBL5435739 | 0.73 | L3MBTL1 (0.52) | NPSR1HPGDKMT2AUSP2HSD17B10 | |
| Formic Acid SCHEMBL28071336 | 0.72 | HSD11B1 (0.53) | KMT2AL3MBTL1 | |
| SCHEMBL3835799 | 0.71 | MEN1 (0.55) | LMNAMAPTRAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009132453-A1 | CYCLYLAMINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD. (CA) | 2009-11-05 | — | — | WO | disclosed |