Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 2/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4401029 | 0.77 | LMNA (0.48) | L3MBTL1KMT2AALDH1A1ATMFKBP1A | |
| SCHEMBL27884072 | 0.75 | AGER (0.54) | L3MBTL1KMT2AHTR2CSLC6A4HDAC3 | |
| SCHEMBL5435739 | 0.74 | L3MBTL1 (0.52) | L3MBTL1KMT2AHTR2CSLC6A4CTSL | |
| SCHEMBL4422666 | 0.73 | NPC1 (0.45) | ALDH1A1AKT1 | |
| SCHEMBL24503910 | 0.72 | L3MBTL1 (0.46) | L3MBTL1KMT2AHTR2CSLC6A4ENPP2 | |
| SCHEMBL10207431 | 0.72 | HSD11B1 (0.56) | L3MBTL1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL8893633 | 0.72 | L3MBTL1 (0.45) | L3MBTL1HTR2CSLC6A4CTSLENPP2 | |
| SCHEMBL18952059 | 0.71 | CTSL (0.48) | L3MBTL1KMT2ACTSLENPP2ALDH1A1 | |
| SCHEMBL6687688 | 0.70 | L3MBTL1 (0.43) | L3MBTL1KMT2AHTR2CSLC6A4ENPP2 | |
| SCHEMBL16095464 | 0.70 | SMN1; SMN2 (0.58) | KMT2AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461308-B1 | BACTERIAL ENZYME INHIBITORS | NOVO PHARMACEUTICALS LTD DE (GB) | 2006-12-20 | — | — | EP | disclosed |
| US-20050182137-A1 | Bacterial enzyme inhibitors | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2005-08-18 | — | — | US | disclosed |
| EP-1495005-A1 | PYRAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | Pfizer Japan Inc. (JP) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003087061-A1 | PYRAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | PFIZER JAPAN INC. (JP) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182137-A1 | Bacterial enzyme inhibitors | DAO, ME1, BLVRB | L3MBTL1 2024/4885KMT2A 3036/4885HTR2C 3447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.