Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL716385 | 0.98 | GRM5 (0.54) | GRM5ALDH1A1CYP2A6CA12CA2 | |
| SCHEMBL1306384 | 0.89 | GABRA1 (0.38) | GRM5ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL1306505 | 0.87 | APP (0.41) | GRM5ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL27134342 | 0.84 | CYP19A1 (0.49) | GRM5ALDH1A1CYP2A6CA12CA2 | |
| SCHEMBL27134344 | 0.84 | GRM5 (0.39) | GRM5ALDH1A1CYP2A6CA12CA2 | |
| SCHEMBL12223988 | 0.84 | GRM5 (0.36) | GRM5ALDH1A1CYP2A6CA12CA2 | |
| SCHEMBL20717546 | 0.84 | GRM5 (0.45) | GRM5ALDH1A1CYP2A6CA12CA2 | |
| SCHEMBL2854252 | 0.82 | CYP1A1 (0.44) | GRM5KCNH2GABRA1GABRG2GABRB3 | |
| SCHEMBL19174201 | 0.80 | CYP1A1 (0.48) | GRM5MAPTGABRA1GABRG2GABRB3 | |
| SCHEMBL5015445 | 0.79 | PTGS2 (0.42) | GRM5ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119119117-A | Method for preparing alkynyl phosphonate by mechanochemical method | 贵州民族大学 | 2024-12-13 | — | — | CN | disclosed |
| US-11766433-B2 | Small molecule inhibitors of the nuclear translocation of androgen receptor for the treatment of castration-resistant prostate cancer | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-09-26 | — | — | US | disclosed |
| CN-116444483-A | Preparation method of 1,3-dithiane substituted diene derivative | 兰州大学 | 2023-07-18 | — | — | CN | disclosed |
| CN-111961052-B | Preparation method of gamma-carboline derivative | 沈阳师范大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-107459438-B | Novel practical nonmetal-catalyzed silica-based deprotection method | 台州学院 | 2020-09-01 | — | — | CN | disclosed |
| US-9649373-B2 | Neoseptins: small molecule adjuvants | THE SCRIPPS INSTITUTE (US) | 2017-05-16 | — | — | US | disclosed |
| US-20160000907-A1 | NEOSEPTINS: SMALL MOLECULE ADJUVANTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-07 | — | — | US | disclosed |
| US-20150144927-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE | NATIONAL UNIVERSITY CORPORATION YAMAGATA UNIVERSITY (JP) | 2015-05-28 | — | — | US | disclosed |
| US-8445695-B2 | Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-05-21 | — | — | US | disclosed |
| US-20120322999-A1 | Synthesis of Phosphono-Substituted Porphyrin Compounds for Attachment to Metal Oxide Surfaces | LINDSEY JONATHAN S (US) | 2012-12-20 | — | — | US | disclosed |
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |
| US-20090234136-A1 | SYNTHESIS OF PHOSPHONO-SUBSTITUTED PORPHYRIN COMPOUNDS FOR ATTACHMENT TO METAL OXIDE SURFACES | LINDSEY JONATHAN S | 2009-09-17 | — | — | US | disclosed |
| US-7553977-B2 | Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-06-30 | — | — | US | disclosed |
| EP-1389626-B1 | Aromatic copolymers of pyrroles and an electroluminescent element using the same | KOREA INST SCI & TECH (KR) | 2008-12-31 | — | — | EP | disclosed |
| US-20080269501-A1 | Synthesis of Phosphono-Substituted Porphyrin Compounds for Attachment to Metal Oxide Surfaces | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-10-30 | — | — | US | disclosed |
| US-7314941-B2 | Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-01-01 | — | — | US | disclosed |
| US-20070055060-A1 | Synthesis of Phosphono-Substituted Porphyrin Compounds for Attachment to Metal Oxide Surfaces | LINDSEY JONATHAN S | 2007-03-08 | — | — | US | disclosed |
| US-6780950-B2 | Pyrrole compounds, polymers thereof and EL element using the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2004-08-24 | — | — | US | disclosed |
| US-20040034189-A1 | Pyrrole compounds, polymers thereof and EL element using the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY | 2004-02-19 | — | — | US | disclosed |
| EP-1389626-A1 | Aromatic copolymers of pyrroles and an electroluminescent element using the same | Korea Institute of Science and Technology (KR) | 2004-02-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269501-A1 | Synthesis of Phosphono-Substituted Porphyrin Compounds for Attachment to Metal Oxide Surfaces | PPOX, DAO, DDO | GRM5 2061/4885ALDH1A1 1570/4885CYP2A6 1097/4885 |
| US-20150144927-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE | LEF1, CORO1A, CORO1C | GRM5 1650/4885ALDH1A1 232/4885CYP2A6 2679/4885 |
| US-20120322999-A1 | Synthesis of Phosphono-Substituted Porphyrin Compounds for Attachment to Metal Oxide Surfaces | PPOX, DAO, DDO | GRM5 2061/4885ALDH1A1 1570/4885CYP2A6 1097/4885 |
| US-20160000907-A1 | NEOSEPTINS: SMALL MOLECULE ADJUVANTS | TLR2, TLR4, TLR1 | GRM5 131/4885ALDH1A1 4691/4885CYP2A6 4280/4885 |
| US-11766433-B2 | Small molecule inhibitors of the nuclear translocation of androgen receptor for the treatment of castration-resistant prostate cancer | AR, NR0B1, NCOA3 | GRM5 1126/4885ALDH1A1 2121/4885CYP2A6 485/4885 |
| US-20090234136-A1 | SYNTHESIS OF PHOSPHONO-SUBSTITUTED PORPHYRIN COMPOUNDS FOR ATTACHMENT TO METAL OXIDE SURFACES | PPOX, DAO, DDO | GRM5 2061/4885ALDH1A1 1570/4885CYP2A6 1097/4885 |
| US-20070055060-A1 | Synthesis of Phosphono-Substituted Porphyrin Compounds for Attachment to Metal Oxide Surfaces | PPOX, DAO, DDO | GRM5 2061/4885ALDH1A1 1570/4885CYP2A6 1097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.