Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4409300 | 0.94 | MAOB (0.44) | MAOBMCHR1SIGMAR1DRD2DRD3 | |
| SCHEMBL4403829 | 0.94 | MAOB (0.44) | MAOBMCHR1LTA4HALDH1A1MEN1 | |
| SCHEMBL4399337 | 0.92 | MAOB (0.41) | MAOBMCHR1LTA4HALDH1A1SIGMAR1 | |
| SCHEMBL4400748 | 0.90 | MAOB (0.37) | MAOBMCHR1ALDH1A1KMT2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL4401842 | 0.90 | MCHR1 (0.36) | MCHR1SIGMAR1HTR1ADRD2DRD3 | |
| SCHEMBL4405941 | 0.90 | HTR1A (0.36) | MAOBLTA4HKMT2AHTR1ADRD2 | |
| SCHEMBL4405632 | 0.90 | MAOB (0.38) | MAOBDRD2DRD3 | |
| SCHEMBL4398599 | 0.89 | ALDH1A1 (0.34) | MAOBMCHR1LTA4HALDH1A1KMT2A | |
| SCHEMBL4396402 | 0.89 | MAOB (0.44) | MAOBMCHR1ALDH1A1MEN1LMNA | |
| SCHEMBL914272 | 0.89 | MAOB (0.47) | MAOBMCHR1LTA4HALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |