Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440060 | 0.87 | BCHE (0.50) | ACHESRCAPPHTR1AADRA1D | |
| SCHEMBL20480283 | 0.83 | SRC (0.47) | SRCGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL25332124 | 0.81 | SRC (0.45) | SRCGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL21947678 | 0.81 | SRC (0.45) | SRCGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL6473683 | 0.81 | HPGDS (0.44) | ACHESRCGABRA1GABRG2GABRB3 | |
| SCHEMBL437945 | 0.81 | ACHE (0.47) | ACHEAPPGABRA1GABRG2GABRB3 | |
| SCHEMBL442249 | 0.80 | NPC1 (0.41) | — | |
| SCHEMBL442268 | 0.78 | ACHE (0.46) | ACHEHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL24010126 | 0.75 | GABRA1 (0.45) | ACHESRCGABRA1GABRG2GABRB3 | |
| SCHEMBL30368021 | 0.75 | PIM1 (0.45) | ACHEAPPGABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |