Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437175 | 0.88 | NPC1 (0.44) | NPC1RAB9ACYP2C9SCN5AGMNN | |
| SCHEMBL439912 | 0.82 | ALOX5AP (0.42) | NPC1RAB9ACYP2C9SCN5AGMNN | |
| SCHEMBL440277 | 0.80 | ACHE (0.50) | — | |
| SCHEMBL9796693 | 0.77 | KDM4E (0.42) | NPC1RAB9ACYP2C9SCN5AGMNN | |
| SCHEMBL30509463 | 0.77 | KDM4E (0.42) | NPC1RAB9ACYP2C9SCN5AGMNN | |
| SCHEMBL438632 | 0.77 | PARP1 (0.45) | CYP1A2CYP3A4NFKB1SMN1; SMN2KIF11 | |
| SCHEMBL438239 | 0.74 | ACHE (0.46) | — | |
| SCHEMBL21143460 | 0.73 | TRPA1 (0.44) | SCN5ASCN9ATRPA1 | |
| SCHEMBL442268 | 0.71 | ACHE (0.46) | LMNATP53CYP3A4GAAALOX15 | |
| SCHEMBL438932 | 0.71 | ACHE (0.46) | JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |