Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | ATP4A | P20648 | 1/20 | 0.42 |
| ▸ | ATP4B | P51164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435849 | 0.81 | HTR1A (0.44) | HTR1AADRA1DADRA1AADRA1BHPGDS | |
| SCHEMBL437559 | 0.80 | HAVCR2 (0.40) | HAVCR2KDM4ECYP3A4 | |
| SCHEMBL441707 | 0.79 | HAVCR2 (0.63) | HAVCR2KDM4EALDH1A1 | |
| SCHEMBL442075 | 0.78 | HAVCR2 (0.46) | HTR1AADRA1DADRA1AADRA1BHAVCR2 | |
| SCHEMBL441668 | 0.77 | GAA (0.41) | G6PDKDM4EALDH1A1 | |
| SCHEMBL439862 | 0.76 | HAVCR2 (0.63) | HAVCR2 | |
| SCHEMBL439519 | 0.75 | DYRK1A (0.39) | G6PDNQO2MCHR1KDM4EALDH1A1 | |
| SCHEMBL2178344 | 0.75 | HTR1A (0.59) | HTR1AADRA1DADRA1AADRA1BG6PD | |
| SCHEMBL441422 | 0.75 | HAVCR2 (0.46) | HAVCR2 | |
| SCHEMBL437767 | 0.75 | HAVCR2 (0.46) | HAVCR2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |