SCHEMBL4404474

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4412232	0.87	KDM4E (0.51)	MEN1KMT2ATSHRKDM4ETP53
	SCHEMBL4406564	0.85	MEN1 (0.45)	MEN1KMT2ATSHRKDM4ETP53
	SCHEMBL4409123	0.84	KDM4E (0.51)	MEN1KMT2ATSHRKDM4ETP53
	SCHEMBL4404505	0.81	CHRM2 (0.53)	MEN1KMT2ATSHRKDM4EALDH1A1
	SCHEMBL14293604	0.81	KDM4E (0.50)	MEN1KMT2ATSHRKDM4ETP53
	SCHEMBL4409089	0.80	CHRM2 (0.57)	MEN1KMT2ATSHRKDM4EALDH1A1
	SCHEMBL4405060	0.80	KDM4E (0.53)	MEN1KMT2AKDM4EPOLB
	SCHEMBL4408353	0.79	PRMT1 (0.52)	TSHRALDH1A1POLBL3MBTL1GAA
	SCHEMBL4414892	0.78	SMARCA2 (0.56)	MEN1KMT2AKDM4ETP53ALDH1A1
	SCHEMBL13921869	0.77	TSHR (0.42)	MEN1KMT2ATSHRKDM4ETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.