SCHEMBL4408353

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4417272	0.90	PRMT1 (0.52)	PRMT1ALDH1A1POLBLMNAGAA
	SCHEMBL4406672	0.89	ALDH1A1 (0.52)	PRMT1ALDH1A1POLBLMNAGAA
	SCHEMBL4406593	0.89	PRMT1 (0.51)	PRMT1ALDH1A1POLBLMNAGAA
	SCHEMBL4414888	0.87	PRMT1 (0.49)	PRMT1ALDH1A1POLBLMNAGAA
	SCHEMBL4412232	0.86	KDM4E (0.51)	ALDH1A1POLBGAASMN1; SMN2TSHR
	SCHEMBL4409123	0.83	KDM4E (0.51)	ALDH1A1POLBSMN1; SMN2TSHRL3MBTL1
	SCHEMBL1169464	0.82	PRMT1 (0.74)	PRMT1ALDH1A1POLBLMNAGAA
	SCHEMBL4404505	0.80	CHRM2 (0.53)	ALDH1A1POLBLMNASMN1; SMN2TSHR
	SCHEMBL4404474	0.79	MEN1 (0.53)	ALDH1A1POLBGAATSHRL3MBTL1
	SCHEMBL4405051	0.78	KCNA5 (0.54)	ALDH1A1CXCR3GAASMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.