Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL587213 | 0.98 | HDAC8 (0.50) | HDAC8ACHEHSD17B10TSHRHRH1 | |
| Hydrochloric Acid SCHEMBL2005070 | 0.96 | HDAC8 (0.48) | HDAC8ACHEHSD17B10TSHRHRH1 | |
| Acetic Acid SCHEMBL15210198 | 0.86 | HDAC8 (0.41) | HDAC8ACHEHSD17B10TSHRHRH1 | |
| Bromide SCHEMBL14811730 | 0.74 | KDM4E (0.40) | HDAC8ACHEKDM4ESMN1; SMN2RAB9A | |
| Bromide SCHEMBL19063544 | 0.74 | HDAC8 (0.44) | HDAC8ACHEHSD17B10TSHRHRH1 | |
| SCHEMBL2233854 | 0.74 | — | — | |
| SCHEMBL4413637 | 0.73 | GABRA1 (0.34) | HDAC8KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL362206 | 0.73 | HDAC8 (0.32) | HDAC8 | |
| SCHEMBL8633170 | 0.73 | ALDH1A1 (0.44) | HDAC8KDM4EALDH1A1MEN1RAB9A | |
| Iodide SCHEMBL9773064 | 0.72 | HDAC8 (0.31) | HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240225003-A1 | PLANT ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF | THE TEXAS A&M UNIVERSITY SYSTEM | 2024-07-11 | — | — | US | disclosed |
| EP-3957177-B1 | FUNGICIDAL AGENT FOR AGRICULTURAL OR HORTICULTURAL USE, PLANT DISEASE CONTROL METHOD, AND PRODUCT FOR PLANT DISEASE CONTROL USE | KUREHA CORP (JP) | 2024-04-03 | — | — | EP | disclosed |
| US-20240065267-A1 | PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLYING THE SAME | MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) | 2024-02-29 | — | — | US | disclosed |
| US-11805779-B2 | Plant disease control composition and method for controlling plant disease by applying the same | MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) | 2023-11-07 | — | — | US | disclosed |
| WO-2023210027-A1 | HIGHLY TRANSMISSIBLE TERMITE CONTROLLING COMPOSITION | ＺＭクロッププロテクション株式会社 | 2023-11-02 | — | — | WO | disclosed |
| EP-3794944-B1 | SAFENER | NIPPON SODA CO (JP) | 2023-10-18 | — | — | EP | disclosed |
| CN-113727606-B | Agricultural/horticultural fungicide, method for controlling plant disease, and product for controlling plant disease | 株式会社吴羽 | 2023-08-15 | — | — | CN | disclosed |
| US-20230192630-A1 | AZOLE DERIVATIVE, METHOD FOR PRODUCING AZOLE DERIVATIVE, AGENT FOR AGRICULTURAL AND HORTICULTURAL USE, AND INDUSTRIAL MATERIAL PROTECTION AGENT | KUREHA CORPORATION (JP) | 2023-06-22 | — | — | US | disclosed |
| EP-3712135-B1 | AZOLE DERIVATIVE, INTERMEDIATE COMPOUND, METHOD FOR PRODUCING AZOLE DERIVATIVE, AGENT FOR AGRICULTURAL AND HORTICULTURAL USE, AND MATERIAL PROTECTION AGENT FOR INDUSTRIAL USE | KUREHA CORP (JP) | 2023-05-03 | — | — | EP | disclosed |
| CN-115052863-B | Azole derivative, process for producing azole derivative, agricultural/horticultural agent, and industrial material protective agent | 株式会社吴羽 | 2023-04-28 | — | — | CN | disclosed |
| US-7335675-B2 | Aqueous suspension formulation for foliar application fungicide | MITSUI CHEMICALS, INC. (JP) | 2008-02-26 | — | — | US | disclosed |
| US-20070224233-A1 | Controlled-Release Agricultural Chemical Formulation | NIPPON SODA CO., LTD (JP) | 2007-09-27 | — | — | US | disclosed |
| WO-2006127298-A2 | METHOD OF PRODUCING SUSPENDED AGRICULTURAL CHEMICAL COMPOSITION | NIPPON SODA CO., LTD. (JP) | 2006-11-30 | — | — | WO | disclosed |
| US-20060270559-A1 | Method of producing suspended agricultural chemical composition | NIPPON SODA CO., LTD. (JP) | 2006-11-30 | — | — | US | disclosed |
| US-20060235066-A1 | Aqueous suspension preparation of bactericide for folieage application | MITSUI CHEMICALS, INC. (JP) | 2006-10-19 | — | — | US | disclosed |
| CN-1826052-A | Aqueous suspension of bactericide for stem and leaf spreading | MITSUI CHEMICALS INC (JP) | 2006-08-30 | — | — | CN | disclosed |
| EP-1649748-A1 | AQUEOUS SUSPENSION PREPARATION OF BACTERICIDE FOR FOLIEAGE APPLICATION | Mitsui Chemicals, Inc. (JP) | 2006-04-26 | — | — | EP | disclosed |
| EP-1283009-A1 | INSECTICIDAL AND ACARICIDAL COMPOSITION | Sumitomo Chemical Company, Limited (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-20030013684-A1 | Agricultural composition | MITSUI CHEMICALS, INC. (JP) | 2003-01-16 | — | — | US | disclosed |
| EP-1258191-A1 | Agricultural composition | Mitsui Chemicals, Inc. (JP) | 2002-11-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240065267-A1 | PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLYING THE SAME | SNX1, HAX1, BROX | ACHE 1863/4885HDAC8 2911/4885HSD17B10 3417/4885 |
| US-11805779-B2 | Plant disease control composition and method for controlling plant disease by applying the same | SNX1, HAX1, BROX | ACHE 1863/4885HDAC8 2911/4885HSD17B10 3417/4885 |
| US-20240225003-A1 | PLANT ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF | DDT, CDA, UROD | ACHE 455/4885HDAC8 4453/4885HSD17B10 1578/4885 |
| US-20230192630-A1 | AZOLE DERIVATIVE, METHOD FOR PRODUCING AZOLE DERIVATIVE, AGENT FOR AGRICULTURAL AND HORTICULTURAL USE, AND INDUSTRIAL MATERIAL PROTECTION AGENT | NOS1, CYP51A1, NOS2 | ACHE 762/4885HDAC8 1384/4885HSD17B10 929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.