SCHEMBL4405261

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11902892	0.75	ALDH1A1 (0.54)	ALDH1A1RARARXRARXRGPTPN1
	SCHEMBL569698	0.73	ECE1 (0.56)	ALDH1A1RARARXRARXRGPTPN1
	SCHEMBL15190506	0.73	GRIN1 (0.36)	DAOKDM4E
	SCHEMBL892878	0.72	ALDH1A1 (0.72)	ALDH1A1RARARXRAPTPN1HPGD
	SCHEMBL619636	0.71	RAB9A (0.62)	ALDH1A1PTPN1HPGDMAPTHTT
	SCHEMBL21523599	0.71	ALDH1A1 (0.51)	ALDH1A1RARARXRARXRGPTPN1
	SCHEMBL23822894	0.70	RAB9A (0.41)	ALDH1A1HPGDMAPTHTTKDM4E
	SCHEMBL11092155	0.70	KDM4E (0.44)	ALDH1A1DAOHPGDMAPTKDM4E
	SCHEMBL1178549	0.69	PTPN1 (0.76)	ALDH1A1RARARXRAPTPN1HPGD
	SCHEMBL12198253	0.69	RARA (0.59)	ALDH1A1RARARXRARXRGPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.