Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | HPGD | P15428 | 3/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.73 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28758615 | 0.98 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10KEAP1 | |
| SCHEMBL3941912 | 0.89 | KEAP1 (0.58) | KDM4EALDH1A1HPGDHSD17B10KEAP1 | |
| SCHEMBL8967268 | 0.89 | KEAP1 (0.58) | KDM4EALDH1A1HPGDHSD17B10KEAP1 | |
| SCHEMBL3996899 | 0.86 | KDM4E (0.70) | KDM4EALDH1A1HPGDHSD17B10KEAP1 | |
| SCHEMBL8967275 | 0.85 | KEAP1 (0.55) | KDM4EALDH1A1HPGDHSD17B10KEAP1 | |
| SCHEMBL29524092 | 0.85 | KEAP1 (0.55) | KDM4EALDH1A1HPGDHSD17B10KEAP1 | |
| SCHEMBL1683930 | 0.85 | KEAP1 (0.55) | KDM4EALDH1A1HPGDHSD17B10KEAP1 | |
| SCHEMBL14934044 | 0.85 | KEAP1 (0.55) | KDM4EALDH1A1HPGDHSD17B10KEAP1 | |
| SCHEMBL22519131 | 0.85 | KEAP1 (0.55) | KDM4EALDH1A1HPGDHSD17B10KEAP1 | |
| SCHEMBL955863 | 0.85 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184679-A | Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| WO-2016071485-A1 | METHOD FOR DETERMINING THE COMPOSITION OF THE SUGAR MOIETY OF A SUGAR CONTAINING COMPOUND | DANMARKS TEKNISKE UNIVERSITET (DK) | 2016-05-12 | — | — | WO | claimed |
| CN-122036604-A | Compound and application thereof | 中国药科大学 | 2026-05-15 | — | — | CN | disclosed |
| CN-122055367-A | 5-Oxo-4, 5-dihydroimidazo [1,5-a ] quinazoline compounds as PI3K [ alpha ] inhibitors | 皮卡维森治疗学股份有限公司 | 2026-05-15 | — | — | CN | disclosed |
| US-12606522-B2 | Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives | ORSOBIO, INC. (US) | 2026-04-21 | — | — | US | disclosed |
| US-12384748-B2 | Modulators of mas-related g-protein receptor X2 and related products and methods | ESCIENT PHARMACEUTICALS, INC. (US) | 2025-08-12 | — | — | US | disclosed |
| WO-2025132758-A1 | PESTICIDALLY ACTIVE QUINAZOLINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-06-26 | — | — | WO | disclosed |
| US-20250154152-A1 | INHIBITORS OF NAEGLERIA FOWLERI | CLEMSON UNIVERSITY | 2025-05-15 | — | — | US | disclosed |
| CN-119977893-A | Preparation method and application of sulfonamide compound for antagonizing NOD1 | 清华大学 | 2025-05-13 | — | — | CN | disclosed |
| WO-2025085474-A1 | 5-OXO-4,5-DIHYDROIMIDAZO[1,5-A]QUINAZOLINE COMPOUNDS AS PI3K[ALPHA] INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |
| US-20250057958-A1 | CYTOTOXICITY TARGETING CHIMERAS FOR CCR2-EXPRESSING CELLS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2025-02-20 | — | — | US | disclosed |
| WO-2001007020-A2 | CARBOXYLIC ACID AMIDES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND THE USE AND PRODUCTION THEREOF | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-02-01 | — | — | WO | disclosed |
| CN-1265109-A | Thiazolobenzoheterocycles, prepn. and medicines containing same | PHONE POULENC RORER S A (FR) | 2000-08-30 | — | — | CN | disclosed |
| US-4760065-A | Trans(-)-10aR-7,8,9,10,10a,11-hexahydro-2-trifluoromethyl -13H-pyrido(1',2':3, 4)imidazo(2, 1b)quinozoline-13-one | HARDTMANN GOETZ E (US) | 1988-07-26 | — | — | US | disclosed |
| EP-0216028-A2 | Use of anthranilic-acid derivatives as anthelmintic medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-01 | — | — | EP | disclosed |
| US-4585772-A | Agents for combating circulatory illnesses and their use | BAYER AKTIENGESELLSCHAFT (DE) | 1986-04-29 | — | — | US | disclosed |
| EP-0053767-B1 | TRICYCLIC CYTOSINE DERIVATIVES FOR USE IN PHARMACEUTICAL PREPARATIONS AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1984-09-12 | — | — | EP | disclosed |
| US-4451464-A | Trifluoromethyl substituted tricyclic quinazolinones useful as tranquilizers | SANDOZ, INC. (US) | 1984-05-29 | — | — | US | disclosed |
| EP-0053767-A1 | Tricyclic cytosine derivatives for use in pharmaceutical preparations and process for their preparation | BAYER AG (DE) | 1982-06-16 | — | — | EP | disclosed |
| US-4307113-A | TREATMENT OF DIABETES | SANDOZ, INC. (US) | 1981-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250057958-A1 | CYTOTOXICITY TARGETING CHIMERAS FOR CCR2-EXPRESSING CELLS | CCR2, CCR1, CCRL2 | KDM4E 4709/4885ALDH1A1 4466/4885HPGD 4538/4885 |
| US-20250154152-A1 | INHIBITORS OF NAEGLERIA FOWLERI | SERPINB1, NAMPT, NIT2 | KDM4E 4091/4885ALDH1A1 1700/4885HPGD 61/4885 |
| US-12606522-B2 | Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives | NR3C2, NR5A1, SRD5A2 | KDM4E 3921/4885ALDH1A1 1507/4885HPGD 2085/4885 |
| US-12384748-B2 | Modulators of mas-related g-protein receptor X2 and related products and methods | MRGPRX2, MRGPRX1, MRGPRX4 | KDM4E 4456/4885ALDH1A1 4827/4885HPGD 1873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.