Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGF2 | P09038 | 3/20 | 0.40 |
| ▸ | FGF1 | P05230 | 2/20 | 0.40 |
| ▸ | VEGFA | P15692 | 2/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.38 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAPDH | P04406 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 2/20 | 0.35 |
| ▸ | SELP | P16109 | 3/20 | 0.35 |
| ▸ | MDK | P21741 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4402910 | 0.97 | FGF2 (0.41) | FGF2FGF1VEGFAHPSENT5E | |
| SCHEMBL4403642 | 0.95 | FGF1 (0.38) | FGF2FGF1VEGFAHPSENT5E | |
| SCHEMBL4402915 | 0.92 | FGF1 (0.39) | FGF2FGF1VEGFAHPSENT5E | |
| SCHEMBL4403646 | 0.88 | SLC6A2 (0.36) | FGF2FGF1VEGFAHPSENT5E | |
| SCHEMBL26562238 | 0.86 | PAX8 (0.38) | PTPN1KMT2AMEN1USP2POLB | |
| SCHEMBL17776090 | 0.85 | PTPN1 (0.39) | NT5EPTPN1SELPPTPN2PTPN11 | |
| SCHEMBL15965619 | 0.85 | TYMP (0.40) | FGF2FGF1VEGFAHPSENT5E | |
| SCHEMBL3700974 | 0.83 | ANTXR2 (0.50) | FGF2FGF1VEGFAHPSENT5E | |
| SCHEMBL16062804 | 0.82 | NT5E (0.38) | FGF2FGF1VEGFAHPSENT5E | |
| SCHEMBL25492659 | 0.82 | PAX8 (0.42) | PTPN1ANTXR2KMT2AMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173606-B2 | Sulfated oligosaccharide derivatives | PROGEN PHARMACEUTICALS LIMITED (AU) | 2012-05-08 | — | — | US | disclosed |
| US-20110130354-A1 | SULFATED OLIGOSACCHARIDE DERIVATIVES | PROGEN PHARMACEUTICALS LIMITED (AU) | 2011-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130354-A1 | SULFATED OLIGOSACCHARIDE DERIVATIVES | HPSE, APOB, LIPG | FGF2 166/4885FGF1 348/4885VEGFA 290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.