Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.55 |
| ▸ | CA9 | Q16790 | 8/20 | 0.55 |
| ▸ | CA12 | O43570 | 7/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | F2 | P00734 | 3/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4408051 | 1.00 | CA2 (0.55) | CA2CA9CA12NPC1RAB9A | |
| SCHEMBL4411222 | 0.87 | NPC1 (0.49) | CA2CA9CA12NPC1RAB9A | |
| SCHEMBL4411219 | 0.87 | NPC1 (0.49) | CA2CA9CA12NPC1RAB9A | |
| SCHEMBL4409635 | 0.82 | MAPT (0.49) | CA2CA9CA12NPC1RAB9A | |
| SCHEMBL4409638 | 0.82 | MAPT (0.49) | CA2CA9CA12NPC1RAB9A | |
| SCHEMBL22047509 | 0.77 | MAPK1 (0.46) | CA2CA9CA12NPC1RAB9A | |
| SCHEMBL22047119 | 0.73 | MAPK1 (0.42) | CA2CA9CA12NPC1RAB9A | |
| SCHEMBL42659 | 0.72 | CA2 (1.00) | CA2CA9CA12NPC1RAB9A | |
| SCHEMBL42643 | 0.72 | CA2 (1.00) | CA2CA9CA12NPC1RAB9A | |
| SCHEMBL4821832 | 0.71 | RECQL (0.50) | CA2CA9CA12RAB9ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318563-A1 | Nematicidal Compositions and Methods | DIVERGENCE, INC. | 2009-12-24 | — | — | US | disclosed |
| WO-2006060654-A2 | PESTICIDAL COMPOSITIONS AND METHODS | DIVERGENCE, INC. (US) | 2006-06-08 | — | — | WO | disclosed |
| US-20050203067-A1 | Pesticidal compositions and methods | DIVERGENCE, INC. | 2005-09-15 | — | — | US | disclosed |
| US-20040254150-A1 | Nematicidal compositions and methods | DIVERGENCE, INC. | 2004-12-16 | — | — | US | disclosed |
| WO-2004103070-A2 | NEMATICIDAL COMPOSITIONS AND METHODS | DIVERGENCE, INC. (US) | 2004-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254150-A1 | Nematicidal compositions and methods | NISCH, PNMT, ATL3 | CA2 3445/4885CA9 3660/4885CA12 3633/4885 |
| US-20050203067-A1 | Pesticidal compositions and methods | ACHE, DDT, PTMS | CA2 701/4885CA9 1371/4885CA12 2113/4885 |
| US-20090318563-A1 | Nematicidal Compositions and Methods | NISCH, PNMT, HNMT | CA2 3350/4885CA9 3556/4885CA12 3398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.