SCHEMBL4409003

SCHEMBL4409003

Cn1nnnc1Cc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.49
MGLL Q99685 2/20 0.46
ALDH1A1 P00352 2/20 0.46
FAAH O00519 1/20 0.46
DAGLA Q9Y4D2 2/20 0.45
DRD2 P14416 1/20 0.43
HTR1A P08908 1/20 0.42
HTR2C P28335 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
LMNA P02545 1/20 0.41
GFER P55789 1/20 0.41
CALM1 P0DP23 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TRPV1 Q8NER1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4834216 0.81 ALDH1A1 (0.45) CNR2MGLLALDH1A1FAAHDRD2
SCHEMBL4408226 0.81 CNR2 (0.57) CNR2MGLLALDH1A1FAAHDAGLA
SCHEMBL3824667 0.81 ALDH1A1 (0.55) CNR2MGLLALDH1A1FAAHDRD2
SCHEMBL25183022 0.80 HTR1A (0.43) DRD2HTR1AHTR2CMEN1KMT2A
SCHEMBL4849385 0.79 HDAC1 (0.49) ALDH1A1MEN1KMT2ALMNATDP1
SCHEMBL4405662 0.79 CNR2 (0.55) CNR2MGLLALDH1A1FAAHMEN1
SCHEMBL7823805 0.78 HTR1A (0.41) CNR2MGLLALDH1A1FAAHDRD2
SCHEMBL20625742 0.77 HTR1A (0.41) CNR2MGLLDAGLADRD2HTR1A
SCHEMBL4413673 0.77 CNR2 (0.45) CNR2MGLLALDH1A1FAAHDAGLA
SCHEMBL4407850 0.77 CNR2 (0.45) CNR2MGLLALDH1A1FAAHDAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9212152-B2 Process for the preparation of N-hydroxy-1-(1-alkyl-1H-tetrazol-5-yl)-1-phenylmethanimine derivatives BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-12-15 US claimed
EP-2812318-B1 PROCESS FOR THE PREPARATION OF N-HYDROXY-1-(1-ALKYL-1H-TETRAZOL-5-YL)-1-PHENYLMETHANIMINE DERIVATIVES BAYER IP GMBH (DE) 2015-10-28 EP claimed
US-20150299145-A1 PROCESS FOR THE PREPARATION OF N-HYDROXY-1-(1-ALKYL-1H-TETRAZOL-5-YL)-1-PHENYLMETHANIMINE DERIVATIVES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-10-22 US claimed
EP-2812318-A1 PROCESS FOR THE PREPARATION OF N-HYDROXY-1-(1-ALKYL-1H-TETRAZOL-5-YL)-1-PHENYLMETHANIMINE DERIVATIVES Bayer Intellectual Property GmbH (DE) 2014-12-17 EP claimed
WO-2013117582-A1 PROCESS FOR THE PREPARATION OF N-HYDROXY-1-(1-ALKYL-1H-TETRAZOL-5-YL)-1-PHENYLMETHANIMINE DERIVATIVES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-08-15 WO claimed
CN-105348324-B Organic phosphorus compound and its synthetic method and application containing tetrazolium heterocycle 河南农业大学 2017-06-30 CN disclosed
WO-2016055802-A1 AGRICULTURAL CHEMICALS REDAG CROP PROTECTION LTD (GB) 2016-04-14 WO disclosed
CN-105348324-A Organophosphorus compounds containing tetrazole heterocycle and synthetic method and application of organophosphorus compound UNIV HENAN AGRICULTURAL 2016-02-24 CN disclosed
US-9212152-B2 Process for the preparation of N-hydroxy-1-(1-alkyl-1H-tetrazol-5-yl)-1-phenylmethanimine derivatives BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-12-15 US disclosed
EP-2812318-B1 PROCESS FOR THE PREPARATION OF N-HYDROXY-1-(1-ALKYL-1H-TETRAZOL-5-YL)-1-PHENYLMETHANIMINE DERIVATIVES BAYER IP GMBH (DE) 2015-10-28 EP disclosed
US-20150299145-A1 PROCESS FOR THE PREPARATION OF N-HYDROXY-1-(1-ALKYL-1H-TETRAZOL-5-YL)-1-PHENYLMETHANIMINE DERIVATIVES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-10-22 US disclosed
EP-2812318-A1 PROCESS FOR THE PREPARATION OF N-HYDROXY-1-(1-ALKYL-1H-TETRAZOL-5-YL)-1-PHENYLMETHANIMINE DERIVATIVES Bayer Intellectual Property GmbH (DE) 2014-12-17 EP disclosed
WO-2013117582-A1 PROCESS FOR THE PREPARATION OF N-HYDROXY-1-(1-ALKYL-1H-TETRAZOL-5-YL)-1-PHENYLMETHANIMINE DERIVATIVES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-08-15 WO disclosed
EP-1859782-B1 Composition for coloring and/or lightening human hair comprising tetrazoles HENKEL AG & CO KGAA (DE) 2009-12-30 EP disclosed
EP-1859782-A1 Composition for coloring and/or lightening human hair comprising tetrazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150299145-A1 PROCESS FOR THE PREPARATION OF N-HYDROXY-1-(1-ALKYL-1H-TETRAZOL-5-YL)-1-PHENYLMETHANIMINE DERIVATIVES HNMT, PNMT, TPH1 CNR2 1185/4885MGLL 3914/4885ALDH1A1 96/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.