Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOST | Q9BQB4 | 1/20 | 0.83 |
| ▸ | FPGS | Q05932 | 2/20 | 0.82 |
| ▸ | GART | P22102 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | DHFR | P00374 | 1/20 | 0.56 |
| ▸ | ATIC | P31939 | 4/20 | 0.55 |
| ▸ | MTHFD1 | P11586 | 2/20 | 0.55 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofolate SCHEMBL29067339 | 0.96 | SOST (0.84) | SOSTFPGSGARTLMNADHFR | |
| Tetrahydrofolate SCHEMBL31346752 | 0.96 | SOST (0.87) | SOSTFPGSGARTLMNADHFR | |
| Tetrahydrofolate SCHEMBL21248602 | 0.96 | SOST (0.87) | SOSTFPGSGARTLMNADHFR | |
| Tetrahydrofolate SCHEMBL8078004 | 0.96 | SOST (0.87) | SOSTFPGSGARTLMNADHFR | |
| Tetrahydrofolate SCHEMBL27678337 | 0.96 | SOST (0.87) | SOSTFPGSGARTLMNADHFR | |
| Tetrahydrofolate SCHEMBL31346753 | 0.96 | SOST (0.87) | SOSTFPGSGARTLMNADHFR | |
| Tetrahydrofolate SCHEMBL31171826 | 0.93 | SOST (0.82) | SOSTFPGSGARTLMNADHFR | |
| Tetrahydrofolate SCHEMBL19376768 | 0.91 | SOST (0.77) | SOSTFPGSGARTLMNADHFR | |
| Tetrahydrofolate SCHEMBL1890563 | 0.91 | SOST (0.77) | SOSTFPGSGARTLMNADHFR | |
| Tetrahydrofolate SCHEMBL19376763 | 0.91 | SOST (0.77) | SOSTFPGSGARTLMNADHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150240226-A1 | NUCLEIC ACIDS AND PROTEINS AND METHODS FOR MAKING AND USING THEM | BP CORP NORTH AMERICA INC (US) | 2015-08-27 | — | — | US | disclosed |
| US-7635572-B2 | Methods for conducting assays for enzyme activity on protein microarrays | Life Technologies Corporation (US) | 2009-12-22 | — | — | US | disclosed |
| EP-1642109-A4 | METHODS FOR CONDUCTING ASSAYS FOR ENZYME ACTIVITY ON PROTEIN MICROARRAYS | PROTOMETRIX INC (US) | 2007-09-05 | — | — | EP | disclosed |
| EP-1642109-A2 | METHODS FOR CONDUCTING ASSAYS FOR ENZYME ACTIVITY ON PROTEIN MICROARRAYS | Protometrix, Inc. (US) | 2006-04-05 | — | — | EP | disclosed |
| US-20050118665-A1 | Methods for conducting assays for enzyme activity on protein microarrays | PROTOMETRIX, INC. | 2005-06-02 | — | — | US | disclosed |
| WO-2005003721-A2 | ENZYME ACTIVITY ASSAYS ON PROTEIN MICROARRAYS | PROTOMETRIX, INC. (US) | 2005-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150240226-A1 | NUCLEIC ACIDS AND PROTEINS AND METHODS FOR MAKING AND USING THEM | POLN, POLM, POLI | SOST 4157/4885FPGS 181/4885GART 591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.