Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLR1A | O95602 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727135 | 0.82 | DRD4 (0.67) | DRD4 | |
| Dimethylamine SCHEMBL9852061 | 0.82 | DRD4 (0.63) | KMT2ADRD4 | |
| Hydrochloric Acid SCHEMBL9343553 | 0.82 | HTR4 (0.48) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL9852142 | 0.80 | CCR1 (0.54) | DRD4NPC1RAB9A | |
| SCHEMBL9727173 | 0.79 | SIGMAR1 (0.57) | DRD4 | |
| SCHEMBL9727123 | 0.79 | DRD4 (0.69) | DRD4 | |
| SCHEMBL9727095 | 0.79 | DRD4 (0.72) | DRD4ALDH1A1 | |
| SCHEMBL9852073 | 0.78 | DRD4 (0.54) | KCNH2KMT2ADRD4KDM4EALDH1A1 | |
| SCHEMBL30569390 | 0.77 | MAOB (0.60) | KCNH2P2RX4KMT2A | |
| SCHEMBL9852082 | 0.76 | DRD4 (0.73) | KCNH2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098915-A | Antiarrhythmia agents | G. D. SEARLE & CO. (US) | 1992-03-24 | — | — | US | claimed |
| EP-0416581-A1 | Substituted N-benzylpiperidine amides | G.D. Searle & Co. (US) | 1991-03-13 | — | — | EP | claimed |