Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4411141 | 0.93 | CCR8 (0.41) | CCR8ACHEFAAHMAPTKMT2A | |
| SCHEMBL4400741 | 0.92 | L3MBTL1 (0.39) | SLC6A3SLC18A2CCR8L3MBTL1FAAH | |
| SCHEMBL4403841 | 0.92 | CCR8 (0.39) | SLC6A3SLC18A2CCR8L3MBTL1FAAH | |
| SCHEMBL4542491 | 0.89 | HTR7 (0.37) | SLC18A2CCR8HTR1ADRD2 | |
| SCHEMBL915248 | 0.88 | KMT2A (0.42) | SLC6A3SLC18A2CCR8GAAKMT2A | |
| SCHEMBL4405829 | 0.85 | PARP1 (0.37) | CCR8ACHEKMT2AHTR1ADRD3 | |
| SCHEMBL4406787 | 0.85 | PARP1 (0.37) | CCR8ACHEKMT2AHTR1ADRD3 | |
| SCHEMBL4394218 | 0.85 | CCR8 (0.41) | CCR8FAAHHTR1ADRD2 | |
| SCHEMBL4404557 | 0.85 | CCR8 (0.43) | CCR8L3MBTL1FAAHMAPTKMT2A | |
| SCHEMBL4399208 | 0.85 | CCR3 (0.39) | SLC6A3SLC18A2CCR8ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |