Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 2/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4403841 | 0.93 | CCR8 (0.39) | L3MBTL1CCR8FAAHSLC6A3SLC18A2 | |
| SCHEMBL4394218 | 0.92 | CCR8 (0.41) | CCR8SOS1FAAHDRD2 | |
| SCHEMBL4411263 | 0.92 | SLC6A3 (0.37) | L3MBTL1CCR8FAAHSLC6A3SLC18A2 | |
| SCHEMBL4409226 | 0.88 | HTR7 (0.40) | CCR8SOS1FAAHDRD2TERT | |
| SCHEMBL4398634 | 0.87 | HTR7 (0.44) | CCR8SOS1DRD2 | |
| SCHEMBL914932 | 0.86 | DRD2 (0.42) | DRD2DRD3 | |
| SCHEMBL4404557 | 0.86 | CCR8 (0.43) | L3MBTL1CCR8SOS1FAAHKDM4E | |
| SCHEMBL4399208 | 0.85 | CCR3 (0.39) | CCR8SOS1SLC6A3SLC18A2DRD2 | |
| SCHEMBL4404435 | 0.85 | TERT (0.39) | FAAHKDM4ERXFP1TERT | |
| SCHEMBL4409097 | 0.85 | CCR8 (0.44) | CCR8FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |