SCHEMBL1004636

SCHEMBL1004636

Brc1cc2c3c(c1)Cc1cccc(c1-3)CC2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.38
HTR2A P28223 1/20 0.38
HTR2C P28335 1/20 0.38
SLC6A4 P31645 1/20 0.38
TDP1 Q9NUW8 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
CYP3A4 P08684 2/20 0.35
TSHR P16473 2/20 0.35
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPN P05981 1/20 0.35
ALOX5 P09917 1/20 0.35
MAPT P10636 1/20 0.35
THRB P10828 1/20 0.35
ALOX15 P16050 1/20 0.35
PTGS1 P23219 1/20 0.35
PDE4A P27815 1/20 0.35
KDR P35968 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4411314 0.91 TDP1 (0.38) SLC6A2HTR2AHTR2CSLC6A4TDP1
SCHEMBL979162 0.87 CYP19A1 (0.32) CYP19A1CYP11B1CYP11B2SRD5A1SRD5A2
SCHEMBL982854 0.82 TSHR (0.46) HTR2AHTR2CTDP1L3MBTL1CYP3A4
SCHEMBL1569413 0.79 PNMT (0.34) TDP1L3MBTL1CYP3A4TSHRCYP19A1
SCHEMBL29388679 0.74 TSHR (0.44) HTR2AHTR2CTDP1L3MBTL1CYP3A4
SCHEMBL5399227 0.74 TSHR (0.52) HTR2AHTR2CTDP1L3MBTL1CYP3A4
SCHEMBL149965 0.74 TSHR (0.44) HTR2AHTR2CTDP1L3MBTL1CYP3A4
SCHEMBL25118730 0.71 ALDH1A1 (0.44) SLC6A2SLC6A4TDP1L3MBTL1ALDH1A1
SCHEMBL18538307 0.70 SLC6A2 (0.40) SLC6A2HTR2AHTR2CSLC6A4TDP1
SCHEMBL1698292 0.69 PTGS2 (0.38) TDP1CYP3A4TSHRALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9773987-B2 Silicon-based compound and organic light-emitting diode comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-09-26 US disclosed
US-9773987-B2 Silicon-based compound and organic light-emitting diode comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-09-26 US disclosed
US-9567287-B2 Compound for organic light-emitting diode and organic light-emitting diode including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-14 US disclosed
US-9567287-B2 Compound for organic light-emitting diode and organic light-emitting diode including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-14 US disclosed
US-9567287-B2 Compound for organic light-emitting diode and organic light-emitting diode including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-14 US disclosed
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed
US-20150349265-A1 AMINE-BASED COMPOUND AND ORGANIC LIGHT- EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-03 US disclosed
US-20150349265-A1 AMINE-BASED COMPOUND AND ORGANIC LIGHT- EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-03 US disclosed
US-7854999-B2 Organoelectroluminescent compound and organoelectroluminescent device employing the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-12-21 US disclosed
US-20090092853-A1 Cyclopentaphenanthrene-based compound and organic light emitting device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2009-04-09 US disclosed
US-20090092853-A1 Cyclopentaphenanthrene-based compound and organic light emitting device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2009-04-09 US disclosed
US-20090092853-A1 Cyclopentaphenanthrene-based compound and organic light emitting device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2009-04-09 US disclosed
US-20080100207-A1 Organoelectroluminescent compound and organoelectroluminescent device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2008-05-01 US disclosed
US-20080100207-A1 Organoelectroluminescent compound and organoelectroluminescent device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2008-05-01 US disclosed
US-20080100207-A1 Organoelectroluminescent compound and organoelectroluminescent device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2008-05-01 US disclosed
US-20080079356-A1 Organoelectroluminescent compound and organoelectroluminescent device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2008-04-03 US disclosed
US-20080079356-A1 Organoelectroluminescent compound and organoelectroluminescent device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2008-04-03 US disclosed
US-20080079356-A1 Organoelectroluminescent compound and organoelectroluminescent device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2008-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090092853-A1 Cyclopentaphenanthrene-based compound and organic light emitting device employing the same ABCB1, ARNT, PPOX SLC6A2 886/4885HTR2A 1619/4885HTR2C 2305/4885
US-20080100207-A1 Organoelectroluminescent compound and organoelectroluminescent device employing the same PPOX, EML4, DDT SLC6A2 4378/4885HTR2A 3616/4885HTR2C 3318/4885
US-20080079356-A1 Organoelectroluminescent compound and organoelectroluminescent device employing the same PPOX, EML4, ALPL SLC6A2 4451/4885HTR2A 3855/4885HTR2C 3538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.