SCHEMBL4412201

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4416110	0.93	MAPT (0.36)	RAB9ACSNK2A2CSNK2BCSNK2A1MAPT
	SCHEMBL4415591	0.90	CA12 (0.37)	KMT2ACYP3A4PTPRB
	SCHEMBL4414309	0.90	TK1 (0.36)	ALDH1A1MEN1KMT2ACYP3A4CYP2C9
	SCHEMBL4421554	0.89	SMN1; SMN2 (0.33)	RAB9ASMN1; SMN2ALDH1A1MAPTMEN1
	SCHEMBL4418646	0.88	DDX3X (0.33)	SMN1; SMN2ALDH1A1MAPTGAAMEN1
	SCHEMBL4426611	0.85	ALDH1A1 (0.33)	ALDH1A1MEN1KMT2A
	SCHEMBL4414797	0.83	TK1 (0.37)	PTPRB
	SCHEMBL4414566	0.83	CA12 (0.38)	CYP3A4PTPRB
	SCHEMBL4411449	0.82	LMNA (0.33)	SMN1; SMN2ALDH1A1MAPTMEN1KMT2A
	SCHEMBL4412301	0.82	KMT2A (0.33)	MEN1KMT2APOLBPTPRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.