Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RGS12 | O14924 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3872555 | 0.85 | GRM5 (0.43) | PPOXGSK3BTDP1CYP3A4MEN1 | |
| SCHEMBL3880489 | 0.83 | PPOX (0.48) | PPOXGSK3BTDP1CYP3A4MEN1 | |
| SCHEMBL30991840 | 0.83 | PPOX (0.39) | PPOXGSK3BTDP1CYP3A4MEN1 | |
| SCHEMBL1424404 | 0.83 | GSK3B (0.40) | PPOXGSK3BTDP1CYP3A4MEN1 | |
| SCHEMBL11028071 | 0.83 | ATAD2 (0.45) | PPOXGSK3BTDP1CYP3A4MEN1 | |
| SCHEMBL24414145 | 0.83 | PPOX (0.39) | PPOXGSK3BTDP1CYP3A4MEN1 | |
| SCHEMBL29835162 | 0.83 | PPOX (0.48) | PPOXGSK3BTDP1CYP3A4MEN1 | |
| SCHEMBL11025056 | 0.78 | S100B (0.46) | GSK3BTDP1CYP3A4MEN1KMT2A | |
| SCHEMBL3884186 | 0.78 | CES1 (0.37) | PPOXGSK3BTDP1CYP3A4MEN1 | |
| SCHEMBL787009 | 0.76 | TDP1 (0.50) | TDP1CYP3A4MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805804-A | Branched cross-linked polyamic acid solution, polyimide adhesive, and preparation method and application thereof | 北京宇程科技有限公司 | 2022-07-29 | — | — | CN | claimed |
| US-20250205374-A1 | METHOD FOR PROVIDING A LABELED SINGLE ISOMERIC CHEMICAL ENTITY TARGETING VECTOR BASED ON THE USE OF AN ISOMER-FREE DIENOPHILE | UNIVERSITY OF COPENHAGEN (DK) | 2025-06-26 | — | — | US | disclosed |
| US-12281099-B2 | Isoindolinone substituted indoles and derivatives as RAS inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2025-04-22 | — | — | US | disclosed |
| WO-2025051721-A1 | METHOD FOR RAPID OXIDATION OF DIHYDROPYRIDAZINES TO PYRIDAZINES | UNIVERSITY OF COPENHAGEN (DK) | 2025-03-13 | — | — | WO | disclosed |
| EP-4520751-A1 | METHOD FOR RAPID OXIDATION OF DIHYDROPYRIDAZINES TO PYRIDAZINES | University of Copenhagen (DK) | 2025-03-12 | — | — | EP | disclosed |
| EP-4490136-A1 | METHOD FOR PROVIDING A LABELED SINGLE ISOMERIC CHEMICAL ENTITY TARGETING VECTOR BASED ON THE USE OF AN ISOMER-FREE DIENOPHILE | University of Copenhagen (DK) | 2025-01-15 | — | — | EP | disclosed |
| CN-113474340-B | Novel isoindolinone substituted indoles and derivatives as RAS inhibitors | 勃林格殷格翰国际有限公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-115368291-B | Fluorescent probe for detecting phosgene and preparation method and use method thereof | 浙江理工大学 | 2024-07-05 | — | — | CN | disclosed |
| CN-115368291-B | Fluorescent probe for detecting phosgene and preparation method and use method thereof | 浙江理工大学 | 2024-07-05 | — | — | CN | disclosed |
| WO-2023170174-A1 | METHOD FOR PROVIDING A LABELED SINGLE ISOMERIC CHEMICAL ENTITY TARGETING VECTOR BASED ON THE USE OF AN ISOMER-FREE DIENOPHILE | UNIVERSITY OF COPENHAGEN (DK) | 2023-09-14 | — | — | WO | disclosed |
| WO-2012037155-A2 | TYROSINE KINASE INHIBITORS | GTX, INC. (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037155-A2 | TYROSINE KINASE INHIBITORS | GTX, INC. (US) | 2012-03-22 | — | — | WO | disclosed |
| US-20120065233-A1 | TYROSINE KINASE INHIBITORS | GREGOR VLAD EDWARD (US) | 2012-03-15 | — | — | US | disclosed |
| US-20120065233-A1 | TYROSINE KINASE INHIBITORS | GREGOR VLAD EDWARD (US) | 2012-03-15 | — | — | US | disclosed |
| US-20120065233-A1 | TYROSINE KINASE INHIBITORS | GREGOR VLAD EDWARD (US) | 2012-03-15 | — | — | US | disclosed |
| US-20110065682-A1 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | MERCK SHARP & DOHME LLC | 2011-03-17 | — | — | US | disclosed |
| US-20110065682-A1 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | MERCK SHARP & DOHME LLC | 2011-03-17 | — | — | US | disclosed |
| US-20100273763-A1 | ORGANOMETALLIC COMPLEXES AS THERAPEUTIC AGENTS | WOMEN & INFANTS HOSPITAL (US) | 2010-10-28 | — | — | US | disclosed |
| US-20100273763-A1 | ORGANOMETALLIC COMPLEXES AS THERAPEUTIC AGENTS | WOMEN & INFANTS HOSPITAL (US) | 2010-10-28 | — | — | US | disclosed |
| WO-2008070557-A2 | ORGANOMETALLIC COMPLEXES AS THERAPEUTIC AGENTS | WOMEN & INFANTS HOSPITAL (US) | 2008-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273763-A1 | ORGANOMETALLIC COMPLEXES AS THERAPEUTIC AGENTS | SCLY, SALL4, AS3MT | PPOX 170/4885GSK3B 2903/4885TDP1 3361/4885 |
| US-12281099-B2 | Isoindolinone substituted indoles and derivatives as RAS inhibitors | NRAS, KRAS, RASSF5 | PPOX 2327/4885GSK3B 1993/4885TDP1 2732/4885 |
| US-20250205374-A1 | METHOD FOR PROVIDING A LABELED SINGLE ISOMERIC CHEMICAL ENTITY TARGETING VECTOR BASED ON THE USE OF AN ISOMER-FREE DIENOPHILE | ALDH3A1, SQLE, DUOX1 | PPOX 46/4885GSK3B 3936/4885TDP1 2846/4885 |
| US-20110065682-A1 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | F9, F12, F8 | PPOX 464/4885GSK3B 571/4885TDP1 3472/4885 |
| US-20120065233-A1 | TYROSINE KINASE INHIBITORS | ALK, ROS1, ABL1 | PPOX 3750/4885GSK3B 442/4885TDP1 282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.