Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | ITGAL | P20701 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 2/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29350035 | 1.00 | MAOA (0.39) | MAOAMAOBPLAULMNAABCG2 | |
| SCHEMBL15704080 | 0.75 | MAOA (0.34) | MAOAMAOBPLAULMNACRHBP | |
| SCHEMBL5782656 | 0.71 | MAOA (0.38) | MAOAMAOBLMNAABCG2ITGB2 | |
| SCHEMBL11394354 | 0.71 | CYP3A4 (0.39) | MAOAMAOB | |
| SCHEMBL2790875 | 0.70 | OXTR (0.39) | MAOAMAOBPLAULMNAABCG2 | |
| SCHEMBL11388095 | 0.67 | BCL2L1 (0.34) | MAOAMAOBLMNATDP1KMT2A | |
| SCHEMBL12043665 | 0.67 | HTR5A (0.35) | — | |
| SCHEMBL7654573 | 0.67 | MAOA (0.43) | MAOAMAOBPLAULMNAKDM4E | |
| SCHEMBL757859 | 0.67 | — | — | |
| SCHEMBL1384118 | 0.67 | MAOA (0.38) | MAOAMAOBPLAUABCG2ITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12030992-B2 | Photocurable composition | CANON KABUSHIKI KAISHA (JP) | 2024-07-09 | — | — | US | claimed |
| CN-116589426-A | Method for synthesizing chiral 1, 3-benzoxazine derivative | 常州大学 | 2023-08-15 | — | — | CN | claimed |
| CN-116283815-B | Preparation method of 1, 3-benzoxazine compound | 嘉实（湖南）医药科技有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-116283815-A | Preparation method of 1, 3-benzoxazine compound | 嘉实（湖南）医药科技有限公司 | 2023-06-23 | — | — | CN | claimed |
| EP-4137543-A1 | COMPOSITION FOR PRODUCING A SHEET-LIKE SEMIFINISHED PRODUCT | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2023-02-22 | — | — | EP | claimed |
| EP-2606037-B1 | NOVEL COMPOSITIONS AND METHODS TO PRODUCE TRIAZINE-ARYLHYDROXY-ALDEHYDE CONDENSATES WITH IMPROVED SOLUBILITY | BAKELITE UK HOLDING LTD (GB) | 2022-05-25 | — | — | EP | claimed |
| CN-113106473-B | Method for preparing 1, 3-benzoxazine derivative through continuous electrochemical microreactor device | 南京工业大学 | 2022-02-18 | — | — | CN | claimed |
| CN-113106473-A | Method for preparing 1, 3-benzoxazine derivative through continuous electrochemical microreactor device | 南京工业大学 | 2021-07-13 | — | — | CN | claimed |
| US-20210147601-A1 | BENZOXAZINE BLENDS | WESTERN WASHINGTON UNIVERSITY (US) | 2021-05-20 | — | — | US | claimed |
| US-10040732-B2 | Process for the production of biaryl compounds | DSM IP ASSETS B.V. (NL) | 2018-08-07 | — | — | US | claimed |
| WO-2012024210-A1 | NOVEL COMPOSITIONS AND METHODS TO PRODUCE TRIAZINE-ARYLHYDROXY-ALDEHYDE CONDENSATES WITH IMPROVED SOLUBILITY | MOMENTIVE SPECIALTY CHEMICALS INC. (US) | 2012-02-23 | — | — | WO | claimed |
| US-20120046424-A1 | NOVEL COMPOSITIONS AND METHODS TO PRODUCE TRIAZINE-ARYLHYDROXY-ALDEHYDE CONDENSATES WITH IMPROVED SOLUBILITY | HEXION SPECIALTY CHEMICALS, INC. | 2012-02-23 | — | — | US | claimed |
| US-7973158-B2 | Method of preparing benzoxazines | HENKEL CORPORATION (US) | 2011-07-05 | — | — | US | claimed |
| EP-1401443-A4 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORP (US) | 2005-10-26 | — | — | EP | claimed |
| US-6905590-B2 | Coating composition containing benzoxazine compound | NIPPON PAINT CO., LTD. (JP) | 2005-06-14 | — | — | US | claimed |
| EP-1401443-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-31 | — | — | EP | claimed |
| WO-2002100849-A2 | NOVEL NITRILES USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | claimed |
| WO-2002098424-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-12-12 | — | — | WO | claimed |
| EP-0356379-B1 | Resins curable into fire-retardant and heat-resistant plastic materials, and method for their preparation | GURIT ESSEX AG (CH) | 1996-03-20 | — | — | EP | claimed |
| EP-0477789-A1 | 1,3-Benzoxazine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-04-01 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10040732-B2 | Process for the production of biaryl compounds | DDT, COASY, ALDH3A1 | MAOA 589/4885MAOB 528/4885PLAU 4655/4885 |
| US-20210147601-A1 | BENZOXAZINE BLENDS | NBAS, UGT1A4, GABRG2 | MAOA 6/4885MAOB 9/4885PLAU 2155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.