SCHEMBL4412921

SCHEMBL4412921

CC1(C)N=C(c2cnc3c(F)cccc3c2)c2cccc(F)c2C1(C)C

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.39
ABCG2 Q9UNQ0 1/20 0.39
KDM4E B2RXH2 4/20 0.36
NPC1 O15118 2/20 0.35
PARP1 P09874 3/20 0.33
ALOX5AP P20292 2/20 0.32
FEN1 P39748 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CASP3 P42574 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
TRPA1 O75762 2/20 0.32
GRIN2B Q13224 1/20 0.31
MBNL1 Q9NR56 1/20 0.30
AKR1C3 P42330 1/20 0.30
AKR1C2 P52895 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29432957 1.00 ABCB1 (0.39) ABCB1ABCG2KDM4ENPC1PARP1
SCHEMBL4416025 0.92 MGAM (0.36) ABCB1ABCG2KDM4ENPC1PARP1
SCHEMBL29919696 0.92 MGAM (0.36) ABCB1ABCG2KDM4ENPC1PARP1
SCHEMBL4507112 0.89 HPGDS (0.42) NPC1ALOX5APFEN1
SCHEMBL318061 0.88 AKR1C3 (0.41) NPC1MBNL1AKR1C3AKR1C2
SCHEMBL29352004 0.88 AKR1C3 (0.41) NPC1MBNL1AKR1C3AKR1C2
Hydrochloric Acid SCHEMBL4531372 0.86 AKR1C3 (0.41) NPC1MBNL1AKR1C3AKR1C2
SCHEMBL29368740 0.84 ABCB1 (0.37) ABCB1ABCG2KDM4ENPC1PARP1
SCHEMBL21295265 0.84 ABCB1 (0.37) ABCB1ABCG2KDM4ENPC1PARP1
SCHEMBL4507256 0.83 L3MBTL1 (0.39) NPC1L3MBTL1CASP3SENP8SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4384016-B1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE BAYER AG (DE) 2025-09-03 EP claimed
CN-118102874-A Active compound combinations and fungicide compositions comprising them 拜耳公司 2024-05-28 CN claimed
US-20240016152-A1 ACTIVE COMPOUND COMBINATIONS BAYER AKTIENGESELLSCHAFT (DE) 2024-01-18 US claimed
US-20230165252-A1 ACTIVE COMPOUND COMBINATIONS BAYER AKTIENGESELLSCHAFT (DE) 2023-06-01 US claimed
EP-4167740-A1 ACTIVE COMPOUND COMBINATIONS Bayer Aktiengesellschaft (DE) 2023-04-26 EP claimed
US-20230111656-A1 METHODS OF CONTROLLING OR PREVENTING INFESTATION OF SOYBEAN PLANTS BY THE PHYTOPATHOGENIC MICROORGANISM CORYNESPORA CASSIICOLA SYNGENTA CROP PROTECTION AG (CH) 2023-04-13 US claimed
EP-4135523-A1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE Bayer Aktiengesellschaft (DE) 2023-02-22 EP claimed
EP-4117436-A1 METHODS OF CONTROLLING OR PREVENTING INFESTATION OF PLANTS BY THE PHYTOPATHOGENIC MICROORGANISM CORYNESPORA CASSIICOLA Syngenta Crop Protection AG (CH) 2023-01-18 EP claimed
CN-115297727-A Method for controlling or preventing plant infection by phytopathogen microorganism corynebacterium polyspora 先正达农作物保护股份公司 2022-11-04 CN claimed
WO-2021255070-A1 ACTIVE COMPOUND COMBINATIONS BAYER AKTIENGESELLSCHAFT (DE) 2021-12-23 WO claimed
EP-2103214-B1 USE OF QUINOLINE COMPOUNDS OR SALTS THEREOF AS ACTIVE INGREDIENTS IN SOIL- OR SEED-TREATING AGENTS AND METHOD FOR CONTROL OF PLANT DISEASE MITSUI CHEMICALS AGRO INC (JP) 2013-10-23 EP claimed
CN-101562975-B Soil treatment agent or seed treatment agent containing quinoline compound or salt thereof as active ingredient, and method for controlling plant disease using same SANKYO AGRO CO LTD 2013-10-23 CN claimed
US-20120282349-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLYING THE SAME MITSUI CHEMICALS AGRO, INC. (JP) 2012-11-08 US claimed
EP-2517562-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES BY APPLYING THE COMPOSITION Mitsui Chemicals Agro, Inc. (JP) 2012-10-31 EP claimed
US-20090325998-A1 SOIL TREATING AGENT OR SEED TREATING AGENT COMPRISING QUINOLINE COMPOUNDS OR SALTS THEREOF AS ACTIVE INGREDIENT,OR METHOD FOR PREVENTING PLANT DISEASES BY USING THE SAME MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2009-12-31 US claimed
US-7632783-B2 fungicides, pesticides for protecting rice crop, tomatoes, cucumbers and green beans; 3-(5-fluoro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)quinoline MITSUI CHEMICALS AGRO, INC. (JP) 2009-12-15 US claimed
CN-101562975-A Soil treatment agent or seed treatment agent containing quinoline compound or salt thereof as active ingredient, and method for controlling plant disease using same SANKYO AGRO CO LTD (JP) 2009-10-21 CN claimed
EP-2103214-A1 SOIL- OR SEED-TREATING AGENT COMPRISING QUINOLINE COMPOUND OR SALT THEREOF AS ACTIVE INGREDIENT, OR METHOD FOR CONTROL OF PLANT DISEASE USING THE SAME Sankyo Agro Company, Limited (JP) 2009-09-23 EP claimed
US-20080275242-A1 3-(Dihydro(Tetrahydro)Isoquinolin-1-Yl)Quinoline Compound MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2008-11-06 US claimed
EP-1736471-A1 3-(DIHYDRO(TETRAHYDRO)ISOQUINOLIN-1-YL)QUINOLINES Sankyo Agro Company, Limited (JP) 2006-12-27 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080275242-A1 3-(Dihydro(Tetrahydro)Isoquinolin-1-Yl)Quinoline Compound QTRT1, RABL3, RECQL ABCB1 1768/4885ABCG2 658/4885KDM4E 1830/4885
US-20240016152-A1 ACTIVE COMPOUND COMBINATIONS CYP51A1, ERG28, BROX ABCB1 411/4885ABCG2 942/4885KDM4E 978/4885
US-20120282349-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLYING THE SAME SNX1, BROX, HAX1 ABCB1 618/4885ABCG2 736/4885KDM4E 2040/4885
US-20230165252-A1 ACTIVE COMPOUND COMBINATIONS CYP51A1, ERG28, BROX ABCB1 411/4885ABCG2 942/4885KDM4E 978/4885
US-20090325998-A1 SOIL TREATING AGENT OR SEED TREATING AGENT COMPRISING QUINOLINE COMPOUNDS OR SALTS THEREOF AS ACTIVE INGREDIENT,OR METHOD FOR PREVENTING PLANT DISEASES BY USING THE SAME RABL3, H1-3, RECQL ABCB1 1410/4885ABCG2 256/4885KDM4E 3837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.