Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4415782 | 0.87 | PREP (0.33) | PREP | |
| SCHEMBL8910403 | 0.82 | TERT (0.36) | TERTLMNA | |
| SCHEMBL29373064 | 0.82 | TERT (0.36) | TERTLMNA | |
| SCHEMBL4413030 | 0.78 | RAB9A (0.39) | TTRLMNA | |
| SCHEMBL3106622 | 0.76 | — | — | |
| SCHEMBL3907426 | 0.75 | MYC (0.41) | TERT | |
| SCHEMBL31163697 | 0.74 | ACHE (0.32) | LMNAPREP | |
| SCHEMBL641602 | 0.74 | ACHE (0.32) | LMNAPREP | |
| Trifluoromethanesulfonic Acid SCHEMBL21542360 | 0.74 | ACHE (0.31) | — | |
| SCHEMBL10518165 | 0.73 | NTSR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1136569-A2 | Nucleic acid probes having highly hydrophilic non-nucleosidic tags with multiple labels, and uses thereof | Bayer Corporation (US) | 2001-09-26 | — | — | EP | disclosed |