Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437507 | 0.79 | MAP4K4 (0.35) | ALOX5APFEN1 | |
| SCHEMBL441422 | 0.79 | HAVCR2 (0.46) | HAVCR2 | |
| SCHEMBL438820 | 0.76 | HAVCR2 (0.39) | HAVCR2DYRK1A | |
| SCHEMBL439646 | 0.74 | HAVCR2 (0.32) | HAVCR2DYRK1A | |
| SCHEMBL436943 | 0.73 | HAVCR2 (0.56) | HAVCR2ALOX5APFEN1 | |
| SCHEMBL436942 | 0.73 | HAVCR2 (0.41) | HAVCR2DYRK1A | |
| SCHEMBL441707 | 0.72 | HAVCR2 (0.63) | HAVCR2DYRK1A | |
| SCHEMBL440416 | 0.71 | CDK8 (0.33) | HAVCR2ALOX5APFEN1 | |
| SCHEMBL437847 | 0.71 | CCR1 (0.42) | HAVCR2DYRK1A | |
| SCHEMBL441974 | 0.69 | HAVCR2 (0.38) | HAVCR2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |