Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442133 | 0.83 | BACE1 (0.41) | HAVCR2NR4A2BACE1ENPP3ENPP1 | |
| SCHEMBL441707 | 0.83 | HAVCR2 (0.63) | HAVCR2NR4A2ACHEALDH1A1CHEK1 | |
| SCHEMBL441422 | 0.79 | HAVCR2 (0.46) | HAVCR2NR4A2ACHE | |
| SCHEMBL442075 | 0.79 | HAVCR2 (0.46) | HAVCR2NR4A2ACHEALDH1A1MEN1 | |
| SCHEMBL441951 | 0.79 | HAVCR2 (0.58) | HAVCR2NR4A2ACHEALDH1A1MEN1 | |
| SCHEMBL441974 | 0.76 | HAVCR2 (0.38) | HAVCR2ALDH1A1MEN1APAF1TDP2 | |
| SCHEMBL437574 | 0.75 | PARP1 (0.45) | HAVCR2NR4A2 | |
| SCHEMBL440440 | 0.75 | HAVCR2 (0.47) | HAVCR2NR4A2ACHEMEN1KMT2A | |
| SCHEMBL436008 | 0.75 | HTR1A (0.44) | HAVCR2ALDH1A1KDM4E | |
| SCHEMBL8488405 | 0.73 | MEN1 (0.63) | HAVCR2ALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |