SCHEMBL4414914

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4420889	0.92	MAOB (0.45)	HIF1AEPAS1LDHALDHBCYP2C9
	SCHEMBL4412370	0.90	L3MBTL1 (0.44)	HTTLMNANPC1RAB9AKMT2A
	SCHEMBL4413699	0.90	GAA (0.48)	HTTALDH1A1LMNANPSR1NPC1
	SCHEMBL4552124	0.89	P2RX3 (0.43)	HTTKDM4EALDH1A1LMNATSHR
	SCHEMBL4420881	0.89	LDHA (0.42)	LDHALDHBHTTKDM4EALDH1A1
	SCHEMBL2170676	0.89	LMNA (0.44)	CYP2C9HTTALDH1A1LMNANPC1
	SCHEMBL4419284	0.89	NPC1 (0.43)	HTTALDH1A1LMNATSHRNPC1
	SCHEMBL4412123	0.89	L3MBTL1 (0.41)	HTTALDH1A1LMNANPC1RAB9A
	SCHEMBL4423907	0.89	HTT (0.50)	HTTKDM4EALDH1A1LMNATSHR
	SCHEMBL4417596	0.89	GAA (0.42)	CYP2C9HTTKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.