SCHEMBL4415882

SCHEMBL4415882

O=C(CCC1NC(=O)OC1=O)OCc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
MAPK1 P28482 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
GLA P06280 1/20 0.44
LMNA P02545 1/20 0.40
CDC25B P30305 1/20 0.39
TDP1 Q9NUW8 2/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A3 Q01959 1/20 0.39
KMT2A Q03164 1/20 0.39
EPHX2 P34913 1/20 0.38
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.38
MMP9 P14780 1/20 0.38
MMP12 P39900 1/20 0.38
IDO1 P14902 1/20 0.38
TDO2 P48775 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7013306 1.00 ALDH1A1 (0.45) ALDH1A1MAPK1L3MBTL1GLALMNA
SCHEMBL12086008 1.00 ALDH1A1 (0.45) ALDH1A1MAPK1L3MBTL1GLALMNA
SCHEMBL22817371 0.92 ALDH1A1 (0.43) ALDH1A1MAPK1L3MBTL1GLALMNA
SCHEMBL11957429 0.87 ALDH1A1 (0.43) ALDH1A1MAPK1L3MBTL1GLALMNA
SCHEMBL9886347 0.86 GLA (0.55) ALDH1A1MAPK1L3MBTL1GLACDC25B
SCHEMBL4413019 0.86 GLA (0.55) ALDH1A1MAPK1L3MBTL1GLACDC25B
SCHEMBL9917628 0.86 GLA (0.55) ALDH1A1MAPK1L3MBTL1GLACDC25B
SCHEMBL22817417 0.84 MEN1 (0.34) GLAKMT2A
SCHEMBL9886333 0.84 MEN1 (0.34) GLAKMT2A
SCHEMBL14901058 0.81 KMT2A (0.38) ALDH1A1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117860908-A Double-drug nano-drug delivery system with cisplatin drug and proteinase K coupled and preparation method thereof 浙江大学长三角智慧绿洲创新中心 2024-04-12 CN claimed
CN-122005788-A Application of polyamino acid material in tumor microwave thermal therapy sensitization 中国科学院理化技术研究所 2026-05-12 CN disclosed
EP-4709361-A1 A COMPOUND FOR PREPARING LIPID NANOPARTICLES ENCAPSULATING AN AGENT, NANOPARTICLE COMPOSITION COMPRISING SAID COMPOUND AND RELATED METHODS THEREOF Agency for Science, Technology and Research (SG) 2026-03-18 EP disclosed
US-12486359-B2 Method for preparing controlled peptide-based polymers and copolymers in an aqueous solution UNIVERSITÉ DE BORDEAUX (FR) 2025-12-02 US disclosed
WO-2024232832-A1 A COMPOUND FOR PREPARING LIPID NANOPARTICLES ENCAPSULATING AN AGENT, NANOPARTICLE COMPOSITION COMPRISING SAID COMPOUND AND RELATED METHODS THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2024-11-14 WO disclosed
CN-117860908-A Double-drug nano-drug delivery system with cisplatin drug and proteinase K coupled and preparation method thereof 浙江大学长三角智慧绿洲创新中心 2024-04-12 CN disclosed
US-20240109875-A1 NOVEL METHOD FOR SYNTHESIZING NCA COMPOUNDS ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER (ENSCM) (FR) 2024-04-04 US disclosed
WO-2024028255-A1 POLY(AMINO ACID) BASED CAPSULES AGFA-GEVAERT NV (BE) 2024-02-08 WO disclosed
US-20230277677-A1 POLYMERIC CONJUGATES AND USES THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2023-09-07 US disclosed
EP-4072530-B1 STIMULI - OR BIO- RESPONSIVE COPOLYMERS, THE POLYMERSOMES COMPRISING THE SAME AND THEIR USE IN DRUG DELIVERY CENTRE NAT RECH SCIENT (FR) 2023-08-30 EP disclosed
US-20100145018-A1 Lipid-Polymer-Conjugates ASTELLAS PHARMA EUROPE BV (NL) 2010-06-10 US disclosed
US-20100145018-A1 Lipid-Polymer-Conjugates ASTELLAS PHARMA EUROPE BV (NL) 2010-06-10 US disclosed
US-20090131589-A1 CONTROLLED MOLECULAR WEIGHT AMINO ACID POLYMERS HAVING FUNCTIONALIZABLE BACKBONES AND END GROUPS AND PROCESSES FOR PREPARING THE SAME UNIVERSITY OF ALABAMA IN HUNTSVILLE 2009-05-21 US disclosed
WO-2009058291-A2 CONTROLLED MOLECULAR WEIGHT AMINO ACID POLYMERS HAVING FUNCTIONALIZABLE BACKBONES AND END GROUPS AND PROCESSES FOR PREPARING THE SAME UNIVERSITY OF ALABAMA IN HUNTSVILLE (US) 2009-05-07 WO disclosed
US-20080069902-A1 Multi-arm polypeptide-poly(ethylene glycol) block copolymers as drug delivery vehicles NEKTAR THERAPEUTICS AL, CORPORATION (US) 2008-03-20 US disclosed
US-20080069902-A1 Multi-arm polypeptide-poly(ethylene glycol) block copolymers as drug delivery vehicles NEKTAR THERAPEUTICS AL, CORPORATION (US) 2008-03-20 US disclosed
US-7316811-B2 Multi-arm polypeptide-poly (ethylene glycol) block copolymers as drug delivery vehicles NEKTAR THERAPEUTICS AL, CORPORATION (US) 2008-01-08 US disclosed
US-7316811-B2 Multi-arm polypeptide-poly (ethylene glycol) block copolymers as drug delivery vehicles NEKTAR THERAPEUTICS AL, CORPORATION (US) 2008-01-08 US disclosed
US-7202954-B2 Target detecting apparatus, target detection method and target detection substrate FUJI PHOTO FILM CO., LTD. (JP) 2007-04-10 US disclosed
US-7202954-B2 Target detecting apparatus, target detection method and target detection substrate FUJI PHOTO FILM CO., LTD. (JP) 2007-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100145018-A1 Lipid-Polymer-Conjugates PARG, GLUL, PHOSPHO1 ALDH1A1 4637/4885MAPK1 4631/4885L3MBTL1 881/4885
US-20230277677-A1 POLYMERIC CONJUGATES AND USES THEREOF CD44, DCLRE1A, CD74 ALDH1A1 2653/4885MAPK1 3732/4885L3MBTL1 528/4885
US-20240109875-A1 NOVEL METHOD FOR SYNTHESIZING NCA COMPOUNDS NPPA, NGLY1, NAAA ALDH1A1 4529/4885MAPK1 2175/4885L3MBTL1 3696/4885
US-20080069902-A1 Multi-arm polypeptide-poly(ethylene glycol) block copolymers as drug delivery vehicles INCENP, IAPP, PGF ALDH1A1 3526/4885MAPK1 3881/4885L3MBTL1 3047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.