Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 16/20 | 0.42 |
| ▸ | SRC | P12931 | 12/20 | 0.42 |
| ▸ | SYK | P43405 | 12/20 | 0.42 |
| ▸ | GSK3A | P49840 | 11/20 | 0.42 |
| ▸ | LCK | P06239 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4416273 | 0.87 | MAPK14 (0.41) | MAPK14SRCSYKGSK3ALCK | |
| SCHEMBL4411102 | 0.86 | MAPK14 (0.42) | MAPK14GSK3A | |
| SCHEMBL4417851 | 0.86 | MAPK14 (0.44) | MAPK14SRCSYKGSK3ALCK | |
| SCHEMBL5490019 | 0.85 | RAB9A (0.42) | MAPK14GSK3A | |
| SCHEMBL4416963 | 0.85 | MAPK14 (0.44) | MAPK14SRCSYKGSK3ALCK | |
| SCHEMBL4417785 | 0.80 | MAPK14 (0.43) | MAPK14GSK3A | |
| SCHEMBL4419919 | 0.80 | SMN1; SMN2 (0.45) | MAPK14SCARB1 | |
| SCHEMBL4412446 | 0.79 | KDR (0.41) | — | |
| SCHEMBL5494587 | 0.78 | MAPK14 (0.42) | MAPK14SRCSYKGSK3ACYP3A4 | |
| SCHEMBL4417658 | 0.78 | MAPT (0.42) | MAPK14SRCSYKGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035005-A2 | THERAPY USING CYTOKINE INHIBITORS | Kemia, INC. (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007146712-A2 | THERAPY USING CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |