Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7018433 | 0.82 | TYMP (0.43) | ALDH1A1HSD17B10HIF1ACYP1B1CES1 | |
| SCHEMBL29874641 | 0.82 | HKDC1 (0.49) | ALDH1A1HSD17B10HIF1ACYP1B1CES1 | |
| SCHEMBL28254837 | 0.80 | SOS1 (0.45) | ALDH1A1HSD17B10HIF1ACYP1B1CES1 | |
| SCHEMBL338172 | 0.80 | CES1 (0.55) | ALDH1A1HSD17B10HIF1ACYP1B1CES1 | |
| SCHEMBL369327 | 0.79 | DNMT1 (0.50) | ALDH1A1HSD17B10HIF1ACYP1B1CES1 | |
| SCHEMBL30125426 | 0.79 | DNMT1 (0.50) | ALDH1A1HSD17B10HIF1ACYP1B1CES1 | |
| SCHEMBL6958036 | 0.78 | GPR84 (0.40) | ALDH1A1HSD17B10HIF1ACES1GPR84 | |
| SCHEMBL1680196 | 0.76 | DHFR (0.43) | ALDH1A1HSD17B10HPGDTSHRDHFR | |
| SCHEMBL7243627 | 0.76 | CES1 (0.52) | ALDH1A1HSD17B10HIF1ACYP1B1CES1 | |
| SCHEMBL29351773 | 0.76 | DHFR (0.43) | ALDH1A1HSD17B10HPGDTSHRDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215893-A | Binaphthyl deep blue light organic material and preparation method and application thereof | 北部湾大学 | 2022-10-21 | — | — | CN | claimed |
| CN-113831628-A | Porous plum blossom pipe and preparation method thereof | 义博通信设备集团股份有限公司 | 2021-12-24 | — | — | CN | claimed |
| CN-111606946-A | Synthetic method of 2,2 '-bis-diphenylphosphino-1, 1' -binaphthyl | 严文忠 | 2020-09-01 | — | — | CN | claimed |
| JP-10130286-A | — | — | None | — | — | JP | disclosed |
| CN-111303011-B | Organic compound, light emitting diode having the same, and light emitting device | 乐金显示有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-115215893-A | Binaphthyl deep blue light organic material and preparation method and application thereof | 北部湾大学 | 2022-10-21 | — | — | CN | disclosed |
| CN-113831628-A | Porous plum blossom pipe and preparation method thereof | 义博通信设备集团股份有限公司 | 2021-12-24 | — | — | CN | disclosed |
| CN-111606946-A | Synthetic method of 2,2 '-bis-diphenylphosphino-1, 1' -binaphthyl | 严文忠 | 2020-09-01 | — | — | CN | disclosed |
| CN-111606946-A | Synthetic method of 2,2 '-bis-diphenylphosphino-1, 1' -binaphthyl | 严文忠 | 2020-09-01 | — | — | CN | disclosed |
| CN-111303011-A | Organic compound, light emitting diode and light emitting device having the same | 乐金显示有限公司 | 2020-06-19 | — | — | CN | disclosed |
| CN-111217714-A | Luminescent material and application thereof | 北京鼎材科技有限公司 | 2020-06-02 | — | — | CN | disclosed |
| US-20040010149-A1 | Ligands for metals and improved metal-catalyzed processes based thereon | NATIONAL SCIENCE FOUNDATION | 2004-01-15 | — | — | US | disclosed |
| EP-1354887-A1 | Ligands for metals and improved metal-catalyzed processes based thereon | Massachusetts Insitute of Technology (US) | 2003-10-22 | — | — | EP | disclosed |
| US-20020156295-A1 | Ligands for metals and improved metal-catalyzed processes based thereon | NATIONAL SCIENCE FOUNDATION | 2002-10-24 | — | — | US | disclosed |
| US-6395916-B1 | AMINE, PHOSPHINE LIGANDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2002-05-28 | — | — | US | disclosed |
| CN-1350768-A | Cyclometallated metal complexes as phosphorescent dopants in organic light emitting devices | UNIV SOUTHERN CALIFORNIA (US) | 2002-05-22 | — | — | CN | disclosed |
| US-6307087-B1 | USE OF CATALYSTS COMPRISING THESE LIGANDS IN TRANSITION METAL-CATALYZED CARBON-HETEROATOM AND CARBON-CARBON BOND-FORMING REACTIONS. | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2001-10-23 | — | — | US | disclosed |
| EP-1097158-A2 | LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000002887-A2 | LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2000-01-20 | — | — | WO | disclosed |
| JP-H10130286-A | NEW OPTICALLY ACTIVE DIPHOSPHINE, ITS DERIVED TRANSITION METAL COMPLEX, AND PRODUCTION OF OPTICALLY ACTIVE SUBSTANCE | TAKASAGO INTERNATL CORP | 1998-05-19 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010149-A1 | Ligands for metals and improved metal-catalyzed processes based thereon | THEM6, SOD1, SLC30A6 | ALDH1A1 2074/4885HSD17B10 1742/4885HIF1A 2637/4885 |
| US-20020156295-A1 | Ligands for metals and improved metal-catalyzed processes based thereon | THEM6, SOD1, SLC30A6 | ALDH1A1 2074/4885HSD17B10 1742/4885HIF1A 2637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.