Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.53 |
| ▸ | CACNB1 | Q02641 | 3/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.53 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4417350 | 0.88 | ESR1 (0.58) | P2RX7ALDH1A1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL4418622 | 0.83 | P2RX7 (0.67) | P2RX7ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL4422476 | 0.82 | HTR7 (0.60) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL4413950 | 0.81 | HTR7 (0.61) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL4419616 | 0.77 | CACNA2D1 (0.53) | ALDH1A1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL4422023 | 0.76 | MAPT (0.60) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL4417108 | 0.74 | ALDH1A1 (0.59) | ALDH1A1USP2MAPK1KMT2AMEN1 | |
| SCHEMBL6160941 | 0.74 | CACNA1G (0.69) | ALDH1A1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL4413975 | 0.74 | ESR1 (0.65) | MAPK1KMT2AMEN1LMNATSHR | |
| SCHEMBL4429576 | 0.73 | HTR1A (0.64) | ALDH1A1KMT2AMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325979-A1 | NOVEL IMIDAZOLYLALKYLCARBONYL DERIVATIVES AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-12-31 | — | — | US | claimed |
| US-8492384-B2 | Imidazolylalkylcarbonyl derivatives as calcium channel modulators and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-07-23 | — | — | US | disclosed |
| US-20090325979-A1 | NOVEL IMIDAZOLYLALKYLCARBONYL DERIVATIVES AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325979-A1 | NOVEL IMIDAZOLYLALKYLCARBONYL DERIVATIVES AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | CACNA1B, CACNA1C, ORAI1 | P2RX7 262/4885ALDH1A1 3972/4885CACNA2D1 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.