SCHEMBL4423692

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4415447	0.92	NPC1 (0.46)	USP30NPC1TSHRPKMALDH1A1
	SCHEMBL4417962	0.92	ALDH1A1 (0.50)	USP30NPC1ALDH1A1MEN1KMT2A
	SCHEMBL4419964	0.91	KDM4C (0.50)	USP30NPC1ALDH1A1MEN1KMT2A
	SCHEMBL4425187	0.90	LMNA (0.55)	USP30NPC1TSHRALDH1A1MEN1
	SCHEMBL4414932	0.90	USP30 (0.48)	USP30NPC1TSHRALDH1A1MEN1
	SCHEMBL4419256	0.89	MAOA (0.50)	USP30NPC1PKMALDH1A1MEN1
	SCHEMBL4415522	0.89	KDM4C (0.48)	USP30NPC1ALDH1A1MEN1KMT2A
	SCHEMBL4422644	0.89	USP30 (0.46)	USP30NPC1TSHRPKMALDH1A1
	SCHEMBL4415073	0.89	L3MBTL1 (0.50)	USP30TSHRALDH1A1MEN1KMT2A
	SCHEMBL4418887	0.88	SMN1; SMN2 (0.48)	USP30NPC1TSHRPKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.