Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1837632 | 0.88 | PTGS2 (0.30) | — | |
| SCHEMBL1832698 | 0.86 | RORC (0.32) | RORCNAMPT | |
| SCHEMBL2408490 | 0.86 | HTR6 (0.35) | GRIA2KCNH2 | |
| SCHEMBL1829458 | 0.86 | RORC (0.32) | RORCNAMPT | |
| SCHEMBL2412509 | 0.85 | — | — | |
| SCHEMBL4425656 | 0.85 | MET (0.39) | — | |
| SCHEMBL4420426 | 0.85 | KMT2A (0.33) | RORC | |
| SCHEMBL1835872 | 0.85 | GRM4 (0.31) | — | |
| SCHEMBL1831693 | 0.84 | — | — | |
| SCHEMBL2410027 | 0.83 | NTRK1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |