SCHEMBL4425679

SCHEMBL4425679

COC(c1ccc(C(=O)C(C)(C)N(C)C)cc1)c1ccc(C(=O)C(C)(C)N(C)C)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34
RARA P10276 1/20 0.34
RARB P10826 1/20 0.34
RARG P13631 1/20 0.34
MLKL Q8NB16 2/20 0.33
NOTUM Q6P988 1/20 0.33
CHEK2 O96017 1/20 0.33
MLYCD O95822 2/20 0.33
NPSR1 Q6W5P4 1/20 0.31
SRC P12931 1/20 0.31
CES1 P23141 1/20 0.31
UTS2R Q9UKP6 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
CYP2D6 P10635 1/20 0.31
HTT P42858 1/20 0.31
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4421841 0.81 ELANE (0.43) ALDH1A1TSHRHSD17B10MLYCDCES1
SCHEMBL3088741 0.81 SRC (0.37) TSHRRARARARBRARGMLKL
SCHEMBL57807 0.81 CYP2C9 (0.44) ALDH1A1TSHRHSD17B10MEN1KMT2A
SCHEMBL4418642 0.80 MLYCD (0.43) ALDH1A1TSHRRARARARBRARG
Methoxymethane SCHEMBL4418025 0.79 SRC (0.36) TSHRRARARARBRARGMLKL
SCHEMBL4427237 0.79 CHRNA7 (0.44) ALDH1A1TSHRHSD17B10MLYCDLMNA
SCHEMBL4425629 0.79 CES1 (0.36) RARARARBRARGMLKLCHEK2
SCHEMBL4427192 0.79 RARA (0.35) ALDH1A1TSHRRARARARBRARG
SCHEMBL4423584 0.79 MLYCD (0.35) TSHRMLYCDCYP2D6LMNA
SCHEMBL57578 0.77 CES2 (0.53) ALDH1A1HSD17B10CES1LMNAELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1620475-B1 NOVEL TRIFUNCTIONAL PHOTOINITIATORS BASF SE (DE) 2009-11-11 EP disclosed
US-7462650-B2 Trifunctional photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-12-09 US disclosed
US-20060270748-A1 Novel trifunctional photoinitiators IGM GROUP B.V. (NL) 2006-11-30 US disclosed
EP-1620475-A1 NOVEL TRIFUNCTIONAL PHOTOINITIATORS Ciba SC Holding AG (CH) 2006-02-01 EP disclosed
WO-2004099262-A1 NOVEL TRIFUNCTIONAL PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-11-18 WO disclosed