Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44344 | 0.85 | TP53 (0.45) | CYP19A1KMT2AMEN1ALDH1A1PKM | |
| SCHEMBL44710 | 0.84 | MEN1 (0.45) | CYP19A1L3MBTL1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL44668 | 0.84 | CYP19A1 (0.56) | CYP19A1KMT2AMEN1CA1CA2 | |
| SCHEMBL38873 | 0.82 | CYP19A1 (0.47) | CYP19A1CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL44653 | 0.80 | ALDH1A1 (0.54) | L3MBTL1CYP1A2CYP3A4KMT2AMEN1 | |
| SCHEMBL22489899 | 0.78 | CYP19A1 (0.73) | CYP19A1L3MBTL1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL44570 | 0.77 | CNR1 (0.40) | CYP19A1KMT2APOLBRAB9APIK3CD | |
| SCHEMBL44400 | 0.77 | ALDH1A1 (0.45) | CYP19A1KMT2APOLBALDH1A1PKM | |
| SCHEMBL5034929 | 0.74 | CYP19A1 (0.74) | CYP19A1L3MBTL1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4349159 | 0.74 | CYP19A1 (0.86) | CYP19A1L3MBTL1CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011137587-A1 | CYTOKINE INHIBITORS | HUTCHISON MEDIPHARMA LIMITED (CN) | 2011-11-10 | — | — | WO | claimed |
| WO-2011137587-A1 | CYTOKINE INHIBITORS | HUTCHISON MEDIPHARMA LIMITED (CN) | 2011-11-10 | — | — | WO | disclosed |
| WO-2011137587-A1 | CYTOKINE INHIBITORS | HUTCHISON MEDIPHARMA LIMITED (CN) | 2011-11-10 | — | — | WO | disclosed |