Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.41 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44570 | 0.88 | CNR1 (0.40) | LMNATP53CYP19A1KMT2ANR3C2 | |
| SCHEMBL44612 | 0.88 | TSHR (0.42) | ALDH1A1CYP19A1KMT2ANR3C2PIK3CD | |
| SCHEMBL44344 | 0.84 | TP53 (0.45) | ALDH1A1LMNAPKMTP53CYP19A1 | |
| SCHEMBL44668 | 0.81 | CYP19A1 (0.56) | ALDH1A1LMNATP53CYP19A1KMT2A | |
| SCHEMBL38873 | 0.78 | CYP19A1 (0.47) | ALDH1A1CYP19A1NR3C2PIK3CDPIK3CG | |
| SCHEMBL12926166 | 0.78 | PIK3CD (0.41) | ALDH1A1TP53CYP19A1KMT2APIK3CD | |
| SCHEMBL44258 | 0.77 | CYP19A1 (0.60) | ALDH1A1PKMCYP19A1KMT2APIK3CD | |
| SCHEMBL22489884 | 0.76 | PRMT6 (0.51) | ALDH1A1LMNASLC12A2SLC12A5PKM | |
| SCHEMBL44139 | 0.76 | ALDH1A1 (0.43) | ALDH1A1LMNASLC12A2SLC12A5TP53 | |
| SCHEMBL38716 | 0.74 | FBP1 (0.47) | ALDH1A1PIK3CDPIK3CGWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011137587-A1 | CYTOKINE INHIBITORS | HUTCHISON MEDIPHARMA LIMITED (CN) | 2011-11-10 | — | — | WO | claimed |
| WO-2011137587-A1 | CYTOKINE INHIBITORS | HUTCHISON MEDIPHARMA LIMITED (CN) | 2011-11-10 | — | — | WO | disclosed |