SCHEMBL442588

SCHEMBL442588

O=COB(O)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV6 Q9H1D0 4/20 0.44
ORAI1 Q96D31 3/20 0.44
ORAI2 Q96SN7 3/20 0.44
ORAI3 Q9BRQ5 3/20 0.44
PCSK9 Q8NBP7 2/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44
CA7 P43166 1/20 0.44
ENPP2 Q13822 1/20 0.44
CA14 Q9ULX7 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
TDP1 Q9NUW8 2/20 0.35
LMNA P02545 2/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
THRB P10828 1/20 0.35
BLM P54132 1/20 0.35
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28812886 0.87 CYP3A4 (0.41) TRPV6ORAI1ORAI2ORAI3PCSK9
SCHEMBL28132197 0.79 TSHR (0.46) CA4CA6CA5ACA7CA14
SCHEMBL393925 0.77 TRPV6 (0.44) TRPV6ORAI1ORAI2ORAI3PCSK9
SCHEMBL13476067 0.76 ORAI1 (0.52) TRPV6ORAI1ORAI2ORAI3PCSK9
SCHEMBL442587 0.76 ORAI1 (0.40) TRPV6ORAI1ORAI2ORAI3PCSK9
SCHEMBL6701242 0.75 HCAR2 (0.41) TRPV6ORAI1ORAI2ORAI3PCSK9
SCHEMBL28895942 0.74 TRPV6 (0.41) TRPV6ORAI1ORAI2ORAI3PCSK9
SCHEMBL27994637 0.74 CYP2A6 (0.44) TDP1LMNAKMT2AMEN1ALDH1A1
SCHEMBL28449656 0.72 ORAI1 (0.39) TRPV6ORAI1ORAI2ORAI3PCSK9
SCHEMBL11904863 0.72 ORAI1 (0.39) TRPV6ORAI1ORAI2ORAI3PCSK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 493 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026042111-A1 TEMPERATURE- AND PH-SENSITIVE, BPA-TARGETED, CHITOSAN–POLY(N-ISOPROPYLACRYLAMIDE)–FPBA CORE-SHELL POLYMERIC NANOPARTICLES CAPABLE OF FORMING COF STRUCTURES FOR USE IN THE BNCT THERAPEUTIC METHOD. SOLEIMANBEIGI MONIREH (IR) 2026-02-26 WO claimed
CN-118955494-A Sulfur-containing thiophene functionalized aldehyde monomer, D-D-A covalent organic framework material and preparation method and application thereof 广东工业大学 2024-11-15 CN claimed
CN-118948744-A Preparation method and application of traditional Chinese medicine monomer hydrogel for treating type I herpes simplex 广西医科大学 2024-11-15 CN claimed
CN-118063863-A Double-functional nano-particle for rapidly detecting sterilizing bacteria and preparation method and application thereof 江苏省农业科学院 2024-05-24 CN claimed
CN-117860664-A Procyanidine injectable hydrogel and preparation method and application thereof 安徽中医药大学 2024-04-12 CN claimed
CN-117771449-A Self-repairable composite anti-adhesion material, and preparation method and application thereof 烟台先进材料与绿色制造山东省实验室 2024-03-29 CN claimed
CN-117462734-A Preparation method and antibacterial application of inorganic-organic compound based on porphyrin 江苏恒正合生命科学有限公司 2024-01-30 CN claimed
CN-117339000-A Preparation method of supermolecule hydrogel material with inherent multifunction 河南师范大学 2024-01-05 CN claimed
CN-112932412-B Self-adhesion electronic skin based on multiple reversible bonding effect and preparation method and application thereof 华南理工大学 2023-10-13 CN claimed
CN-114865097-B Polymer electrolyte based on boric acid transesterification reaction, preparation method and application thereof 华中科技大学 2023-07-25 CN claimed
WO-2006045310-A1 LAUNDRY BARS WITH IMPROVED STORAGE STABILITY NOVOZYMES A/S (DK) 2006-05-04 WO claimed
EP-1343792-B1 METHOD FOR PRODUCING FORMYLPHENYLBORONIC ACIDS CLARIANT GMBH (DE) 2005-02-02 EP claimed
US-6833470-B2 Reaction of protected chlorobenzaldehydes with lithium in an inert solvent and reacting lithiated product with a trihalo-, trialkoxy-, trialkylthio- or tris(dialkylamino)- borane CLARIANT GMBH (DE) 2004-12-21 US claimed
US-20040049050-A1 Method for producing formylphenylboronic acids EUTICALS GMBH (DE) 2004-03-11 US claimed
US-20030176709-A1 Vinyl-phenyl pyridine monomers and polymers prepared thereform KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY 2003-09-18 US claimed
US-6545159-B2 Suzuki coupling reaction of vinyl-phenylboronic acid and 2-bromopyridine in presence of alkali metallic base and tetrakis/triphenylphosphine/palladium to form styrenepyridine monomer KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2003-04-08 US claimed
US-20030055283-A1 Process for preparing highly pure formylphenylboronic acids CLARIANT GMBH 2003-03-20 US claimed
US-20020198346-A1 Vinyl-phenyl pyridine monomers and polymers prepared thereform KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY 2002-12-26 US claimed
US-6420597-B2 ACIDIFICATION, SEPARATION, PRECIPITATION CLARIANT GMBH (DE) 2002-07-16 US claimed
US-20020010332-A1 Process for preparing highly pure formylphenyboronic acids CLARIANT GMBH 2002-01-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030055283-A1 Process for preparing highly pure formylphenylboronic acids PAH, PEAK1, FGFR1 TRPV6 572/4885ORAI1 201/4885ORAI2 3010/4885
US-20020010332-A1 Process for preparing highly pure formylphenyboronic acids PAH, PEAK1, FGFR1 TRPV6 622/4885ORAI1 182/4885ORAI2 2909/4885
US-20020198346-A1 Vinyl-phenyl pyridine monomers and polymers prepared thereform VAT1, PBRM1, THEM6 TRPV6 53/4885ORAI1 1424/4885ORAI2 1969/4885
US-20030176709-A1 Vinyl-phenyl pyridine monomers and polymers prepared thereform VAT1, PBRM1, THEM6 TRPV6 53/4885ORAI1 1424/4885ORAI2 1969/4885
US-20040049050-A1 Method for producing formylphenylboronic acids MAOB, BLVRB, FOSB TRPV6 465/4885ORAI1 3881/4885ORAI2 4320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.