SCHEMBL442712

SCHEMBL442712

Oc1ccccc1-c1ccc2c(c1-c1ccccc1O)Cc1ccccc1-2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.46
PGR P06401 1/20 0.42
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
DRD2 P14416 2/20 0.39
DRD1 P21728 1/20 0.39
DRD5 P21918 1/20 0.39
DRD3 P35462 1/20 0.39
ALDH1A1 P00352 4/20 0.38
MAPT P10636 3/20 0.38
KDM4E B2RXH2 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HPGD P15428 2/20 0.38
HTR7 P34969 2/20 0.38
HTR2B P41595 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
LMNA P02545 1/20 0.38
SRD5A2 P31213 1/20 0.38
CA1 P00915 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31623885 1.00 PNMT (0.46) PNMTPGRNPC1RAB9ADRD2
Benzene SCHEMBL18983267 0.98 PNMT (0.45) PNMTPGRNPC1RAB9ADRD2
Phenol SCHEMBL4631641 0.95 PNMT (0.42) PNMTPGRNPC1RAB9ADRD2
SCHEMBL8840926 0.88 ALDH1A1 (0.46) PNMTPGRNPC1RAB9AALDH1A1
SCHEMBL382855 0.85 PNMT (0.56) PNMTNPC1RAB9ADRD2DRD1
SCHEMBL1233464 0.83 PNMT (0.40) PNMTPGRNPC1RAB9ADRD2
SCHEMBL19326641 0.82 PNMT (0.47) PNMTPGRNPC1RAB9ADRD2
SCHEMBL30855380 0.81 PGR (0.43) PNMTPGRNPC1RAB9ADRD2
SCHEMBL813189 0.81 CA12 (0.46) PNMTPGRNPC1RAB9ADRD2
SCHEMBL30163133 0.81 PNMT (0.52) PNMTPGRNPC1RAB9ADRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 383 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210363289-A1 RESIN COMPOSITIONS AND RESIN INFUSION PROCESS CYTEC INDUSTRIES INC. (US) 2021-11-25 US claimed
EP-3700957-A2 RESIN COMPOSITIONS AND RESIN INFUSION PROCESS Cytec Industries Inc. (US) 2020-09-02 EP claimed
CN-111295407-A Resin composition and resin infusion method 塞特工业公司 2020-06-16 CN claimed
US-20190127514-A1 RESIN COMPOSITIONS AND RESIN INFUSION PROCESS CYTEC INDUSTRIES INC. (US) 2019-05-02 US claimed
US-20170174835-A1 FLUORENYLIDENE-DIPHENOL-CONTAINING POLYPHENYLENE OXIDE ELITE ELECTRONIC MATERIAL (KUNSHAN) CO., LTD. (CN) 2017-06-22 US claimed
US-20080027244-A1 Method for Manufacturing Aromatic Dicarboxylic Acid JFE CHEMICAL CORPORATION (JP) 2008-01-31 US claimed
US-20070255075-A1 Aromatic Diamine And Method For Manufacturing Same JFE CHEMICAL CORPORATION (JP) 2007-11-01 US claimed
EP-1834943-A1 PROCESS FOR PRODUCING AROMATIC DICARBOXYLIC ACID JFE Chemical Corporation (JP) 2007-09-19 EP claimed
EP-1803705-A1 AROMATIC DIAMINE AND PROCESS FOR PRODUCING THE SAME JFE Chemical Corporation (JP) 2007-07-04 EP claimed
EP-1247142-A4 ELECTROPHOTOGRAPHIC PHOTOCONDUCTORS COMPRISING POLYARYL ETHERS LEXMARK INT INC (US) 2006-06-07 EP claimed
WO-1993009074-A2 CHLORINATION PROCESS, ALKYLATION OF PRODUCTS OF SAID PROCESS AND SOME PRODUCTS THEREOF THE DOW CHEMICAL COMPANY (US) 1993-05-13 WO claimed
US-5200496-A Adding chain terminator and catalyst to control molecular weight THE DOW CHEMICAL COMPANY (US) 1993-04-06 US claimed
US-5196479-A IMPACT RESISTANT BLENDS OF HIGH HEAT POLYCARBONATE AND AROMATIC POLYESTER THE DOW CHEMICAL COMPANY (US) 1993-03-23 US claimed
WO-1992015643-A1 IMPACT RESISTANT BLENDS OF HIGH HEAT POLYCARBONATE AND AROMATIC POLYESTER THE DOW CHEMICAL COMPANY (US) 1992-09-17 WO claimed
WO-1992014787-A1 BLENDS OF THERMOPLASTIC MOLDING COMPOSITIONS CONTAINING EPOXY RESINS THE DOW CHEMICAL COMPANY (US) 1992-09-03 WO claimed
EP-0258504-B1 FLUORENE POLYARYLATE POLYMERS AND ALLOY COMPOSITIONS THEREOF CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1991-11-06 EP claimed
US-4983672-A Containing 9,9-bis(hydroxyphenyl)fluorene MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-01-08 US claimed
EP-0325058-A1 Improved epoxide resin compositions and method MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-07-26 EP claimed
EP-0258504-A1 Fluorene polyarylate polymers and alloy compositions thereof CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1988-03-09 EP claimed
US-4612350-A Bis(hydroxyphenyl)fluorene polyarylate polymers and alloys CHEVRON RESEARCH COMPANY (US) 1986-09-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080027244-A1 Method for Manufacturing Aromatic Dicarboxylic Acid DDC, PAH, ALDH7A1 PNMT 3850/4885PGR 4782/4885NPC1 1846/4885
US-20070255075-A1 Aromatic Diamine And Method For Manufacturing Same AOC1, DDC, PADI1 PNMT 179/4885PGR 2050/4885NPC1 4744/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.