Biphenyl

Biphenyl

SCHEMBL4430290

OCC1CCCN1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.51
LTA4H P09960 7/20 0.50
CHRNB4 P30926 1/20 0.44
CHRNA3 P32297 1/20 0.44
HTR6 P50406 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL5439264 1.00 POLB (0.51) POLBLTA4HCHRNB4CHRNA3HTR6
Biphenyl SCHEMBL16732521 0.88 LTA4H (0.45) POLBLTA4HCHRNB4CHRNA3
SCHEMBL9015256 0.86 POLB (0.57) POLBLTA4H
SCHEMBL8135451 0.84 POLB (0.47) POLBLTA4HCHRNB4CHRNA3HTR6
SCHEMBL115932 0.82
SCHEMBL7787365 0.82 FDPS (0.41) POLBCHRNB4CHRNA3
SCHEMBL10141198 0.82
SCHEMBL10141207 0.82
SCHEMBL19071 0.82
SCHEMBL145266 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113943317-B Preparation method of MeCBS solid 大连双硼医药化工有限公司 2024-02-27 CN claimed
CN-114853662-B Process for preparing chiral hydrazinopiperidine derivatives 四川青木制药有限公司 2024-01-12 CN claimed
CN-114853662-A Preparation method of chiral hydrazinylpiperidine derivative 四川青木制药有限公司 2022-08-05 CN claimed
CN-107188771-B Chiral synthesis method of gamma-nitrophenol compound 浙江工业大学 2021-08-24 CN claimed
CN-109265385-B Synthesis process of chiral catalyst 上海福乐医药科技有限公司 2020-10-27 CN claimed
CN-103772224-B Preparation method of D-threonine CHENGDU BAISHIXING SCIENCE AND TECHNOLOGY INDUSTRY CO LTD 2015-04-15 CN claimed
CN-103772224-A Preparation method of D-threonine CHENGDU BAISHIXING SCIENCE AND TECHNOLOGY INDUSTRY CO LTD 2014-05-07 CN claimed
CN-120623134-A Dihydromyricetin-diphenyl prolinol chiral eutectic as well as preparation method and application thereof 天津大学 2025-09-12 CN disclosed
CN-120623134-A Dihydromyricetin-diphenyl prolinol chiral eutectic as well as preparation method and application thereof 天津大学 2025-09-12 CN disclosed
CN-120623095-A Crystalline as a racemic compound Deracemization method for chiral compound 天津大学 2025-09-12 CN disclosed
EP-4140992-B1 METHOD FOR PREPARING S-NICOTINE SHENZHEN ZINWI BIO TECH CO LTD (CN) 2024-10-16 EP disclosed
EP-4144727-B1 METHOD FOR PREPARING CHIRAL SYNTHETIC NICOTINE SHENZHEN ZINWI BIO TECH CO LTD (CN) 2024-10-09 EP disclosed
EP-4144726-B1 PREPARATION METHOD FOR SYNTHESIZING S-NICOTINE FROM GLUTARIC ACID ESTER SHENZHEN ZINWI BIO TECH CO LTD (CN) 2024-10-02 EP disclosed
EP-2132179-A1 PROCESS FOR PREPARING ISOMERS OF CARMOTEROL Cipla Limited (IN) 2009-12-16 EP disclosed
WO-2008104781-A1 PROCESS FOR PREPARING ISOMERS OF CARMOTEROL CIPLA LIMITED (IN) 2008-09-04 WO disclosed
US-20080200672-A1 Highly enantioselective carbonyl reduction with borane catalyzed by chiral spiroborate esters derived from chiral beta-aminoalcohols NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2008-08-21 US disclosed
US-20070232813-A1 Substituted Cyclohexadienals - Syntheses and Applications THE TEXAS A&M UNIVERSITY SYSTEM 2007-10-04 US disclosed
CN-1156448-C Optical isomer of 3-methyl fentanyl, derivant, synthesizing and its analgesic activity 中国科学院上海药物研究所 2004-07-07 CN disclosed
CN-1371903-A Optical isomer of 3-methyl fentanyl, derivant, synthesizing and its analgesic activity SHANGHAI INST OF DRUG CHINESE (CN) 2002-10-02 CN disclosed
US-5527923-A Process for preparing enantiomerically pure diarylprolinols BOEHRINGER INGELHEIM KG (DE) 1996-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070232813-A1 Substituted Cyclohexadienals - Syntheses and Applications DHPS, COASY, PPIE POLB 702/4885LTA4H 659/4885CHRNB4 4740/4885
US-20080200672-A1 Highly enantioselective carbonyl reduction with borane catalyzed by chiral spiroborate esters derived from chiral beta-aminoalcohols ADH1A, ALDH7A1, HSD11B1 POLB 1177/4885LTA4H 3345/4885CHRNB4 801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.