Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 10/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | F13A1 | P00488 | 1/20 | 0.56 |
| ▸ | TGM1 | P22735 | 1/20 | 0.56 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18753609 | 0.85 | TGM2 (0.64) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL29277083 | 0.82 | PTGS2 (0.55) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL782552 | 0.82 | TGM2 (1.00) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL21300143 | 0.82 | TGM2 (0.64) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL14341775 | 0.82 | TGM2 (0.86) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL439369 | 0.81 | TGM2 (0.79) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL9006430 | 0.80 | TGM2 (0.61) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL10504965 | 0.80 | TGM2 (0.60) | TGM2LMNAF13A1TGM1TGM3 | |
| SCHEMBL6358305 | 0.80 | TGM2 (0.71) | TGM2LMNAF13A1TGM1TGM3 | |
| Diacetamate SCHEMBL863106 | 0.80 | KMT2A (0.81) | LMNAMEN1KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3284469-B1 | COMPOSITIONS AND METHODS FOR DETECTION OF LYSOSOMAL STORAGE DISEASE | GENZYME CORP (US) | 2020-11-04 | — | — | EP | disclosed |
| EP-3284469-A2 | COMPOSITIONS AND METHODS FOR DETECTION OF LYSOSOMAL STORAGE DISEASE | Genzyme Corporation (US) | 2018-02-21 | — | — | EP | disclosed |
| EP-2535050-B1 | Compositions and methods for detection of lysosomal storage disease | GENZYME CORP (US) | 2017-07-05 | — | — | EP | disclosed |
| US-8431335-B2 | Glucosyl ceramide, sodium taurocholate, and buffer; bioassays | GENZYME CORPORATION (US) | 2013-04-30 | — | — | US | disclosed |
| EP-2535050-A2 | Compositions and methods for detection of lysosomal storage disease | GENZYME CORPORATION (US) | 2012-12-19 | — | — | EP | disclosed |
| EP-2061477-A2 | COMPOSITIONS AND METHODS FOR DETECTION OF LYSOSOMAL STORAGE DISEASE | Genzyme Corporation (US) | 2009-05-27 | — | — | EP | disclosed |
| US-20080248512-A1 | Methods for detection of lysosomal storage disease | GENZYME CORPORATION (US) | 2008-10-09 | — | — | US | disclosed |
| US-20080248513-A1 | Methods for detection of lysosomal storage disease | GENZYME CORPORATION | 2008-10-09 | — | — | US | disclosed |
| US-20080145836-A1 | Compositions and methods for detection of lysosomal storage disease | GENZYME CORPORATION (US) | 2008-06-19 | — | — | US | disclosed |
| WO-2008033427-A2 | COMPOSITIONS AND METHODS FOR DETECTION OF LYSOSOMAL STORAGE DISEASE | GENZYME CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |