SCHEMBL9006430

SCHEMBL9006430

C=CC(=O)Nc1ccc(OC(F)=C(F)F)cc1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 12/20 0.61
F13A1 P00488 2/20 0.53
TGM1 P22735 2/20 0.53
LMNA P02545 1/20 0.53
TGM3 Q08188 1/20 0.53
MAP2K7 O14733 1/20 0.44
THRA P10827 1/20 0.42
THRB P10828 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
ALDH1A1 P00352 2/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TEK Q02763 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4431772 0.80 TGM2 (0.70) TGM2F13A1TGM1LMNATGM3
SCHEMBL15510891 0.80 MEN1 (0.47) LMNATHRBMEN1KMT2AALDH1A1
SCHEMBL9006567 0.79 THRB (0.51) TGM2LMNATHRATHRBMEN1
SCHEMBL14341775 0.79 TGM2 (0.86) TGM2F13A1TGM1LMNATGM3
SCHEMBL439369 0.78 TGM2 (0.79) TGM2F13A1TGM1LMNATGM3
SCHEMBL18753609 0.76 TGM2 (0.64) TGM2F13A1TGM1LMNATGM3
SCHEMBL21300143 0.76 TGM2 (0.64) TGM2F13A1TGM1LMNATGM3
SCHEMBL9006408 0.76 RXFP1 (0.51) LMNATHRBMEN1KMT2AALDH1A1
SCHEMBL782552 0.76 TGM2 (1.00) TGM2F13A1TGM1LMNATGM3
SCHEMBL30459766 0.75 KMT2A (0.68) TGM2F13A1TGM1LMNATGM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5489623-A APPLYING POLYMER TO SURFACE, EXPOSING TO INCIDENT PHOTONICRADIATION TO RENDER PORTIONS LESS SOLUBLE OR DISPERSIBLE THE DOW CHEMICAL COMPANY (US) 1996-02-06 US claimed
EP-0676062-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1995-10-11 EP claimed
US-5426164-A Solvent and chemical resistant coatings and photoresists; photocuring of perfluorovinyl polymers containing photo active sites; cyclization THE DOW CHEMICAL COMPANY (US) 1995-06-20 US claimed
WO-1994015258-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1994-07-07 WO claimed
US-5489623-A APPLYING POLYMER TO SURFACE, EXPOSING TO INCIDENT PHOTONICRADIATION TO RENDER PORTIONS LESS SOLUBLE OR DISPERSIBLE THE DOW CHEMICAL COMPANY (US) 1996-02-06 US disclosed
EP-0676062-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1995-10-11 EP disclosed
US-5426164-A Solvent and chemical resistant coatings and photoresists; photocuring of perfluorovinyl polymers containing photo active sites; cyclization THE DOW CHEMICAL COMPANY (US) 1995-06-20 US disclosed
WO-1994015258-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1994-07-07 WO disclosed