SCHEMBL4431958

SCHEMBL4431958

COC(=O)CCCCc1ccc(O)c(Cl)c1O

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.40
MAPT P10636 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
TYR P14679 1/20 0.39
KAT2B Q92831 2/20 0.38
MIF P14174 1/20 0.38
CYP4F2 P78329 1/20 0.38
CYP4A11 Q02928 1/20 0.38
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2345176 0.89 KMT2A (0.40) TSHRMAPTL3MBTL1KAT2BLMNA
SCHEMBL15876199 0.77 MAPT (0.46) HPGDMAPTL3MBTL1KAT2BMIF
SCHEMBL4418335 0.76 TYR (0.57) TSHRMAPTTYR
SCHEMBL28747388 0.75 CYP4F2 (0.55) HPGDTSHRCYP4F2CYP4A11LMNA
SCHEMBL31155814 0.75 CYP4F2 (0.55) HPGDTSHRCYP4F2CYP4A11LMNA
SCHEMBL9129463 0.75 HPGD (0.52) HPGDTSHRMAPTTYR
SCHEMBL27551717 0.74 IAPP (0.49)
SCHEMBL70495 0.74 TYR (0.56) HPGDTSHRMAPTTYR
SCHEMBL9128626 0.74 ALDH1A1 (0.55) HPGDTYRMIF
SCHEMBL10732614 0.73 CNR1 (0.44) HPGDTSHRMAPTL3MBTL1KAT2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7541454-B2 Compounds and methods for fluorescent labeling EPOCH BIOSCIENCES, INC. (US) 2009-06-02 US disclosed
US-7541454-B2 Compounds and methods for fluorescent labeling EPOCH BIOSCIENCES, INC. (US) 2009-06-02 US disclosed
US-7541454-B2 Compounds and methods for fluorescent labeling EPOCH BIOSCIENCES, INC. (US) 2009-06-02 US disclosed
US-20050159606-A1 Compounds and methods for fluorescent labeling EPOCH BIOSCIENCES, INC. (US) 2005-07-21 US disclosed
WO-2005040357-A2 COMPOUNDS AND METHODS FOR FLUORESCENT LABELING EPOCH BIOSCIENCES, INC. (US) 2005-05-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050159606-A1 Compounds and methods for fluorescent labeling TFEB, HLCS, PFAS HPGD 1511/4885TSHR 4324/4885MAPT 1854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.