Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938546 | 0.81 | NPSR1 (0.50) | KDM4EKMT2ARAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL8387202 | 0.79 | NPSR1 (0.43) | KDM4EKMT2AL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9804612 | 0.78 | CES2 (0.38) | KDM4EKMT2ARAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL4433309 | 0.78 | NPSR1 (0.41) | KDM4EKMT2ARAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL8061570 | 0.77 | ALDH1A1 (0.46) | KDM4EKMT2ARAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL9623703 | 0.76 | NPSR1 (0.45) | KDM4EKMT2ARAB9ASMN1; SMN2HPGD | |
| SCHEMBL6672016 | 0.75 | HSD11B1 (0.48) | KDM4EKMT2ARAB9ASMN1; SMN2HPGD | |
| SCHEMBL22680922 | 0.74 | ALDH1A1 (0.46) | KDM4EKMT2ARAB9ASMN1; SMN2HPGD | |
| SCHEMBL11742976 | 0.74 | L3MBTL1 (0.40) | KDM4EKMT2ARAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL9804578 | 0.74 | KMT2A (0.42) | KDM4EKMT2ASMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5227504-A | Trialkylsilylating agent and process for preparing N,N-disubstituted aminotrialkylsilane using the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |