Water

Water

SCHEMBL4433965

CCOC(C)O.O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27614609 0.97
SCHEMBL27720603 0.97 LMNA (0.53)
SCHEMBL15882 0.97
SCHEMBL12087712 0.97
Iodide SCHEMBL8161945 0.93
Hydrochloric Acid SCHEMBL16753000 0.93
SCHEMBL29712488 0.93 LMNA (0.50)
Ammonia Solution, Strong SCHEMBL11833381 0.93
SCHEMBL5763450 0.93
Methane SCHEMBL3663242 0.93

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1142803-C Intumescent flame retardant compositions for high temperature and long term protection 2004-03-24 CN claimed
CN-1294528-A Intumescent fire-retardant compsn. for high temp and long duration protection NO FIRE TECH INC (US) 2001-05-09 CN claimed
US-11814401-B2 Luminescent material and electroluminescent display device using the same LG DISPLAY CO., LTD (KR) 2023-11-14 US disclosed
US-11495755-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-11-08 US disclosed
US-20210198298-A1 LUMINESCENT MATERIAL AND ELECTROLUMINESCENT DISPLAY DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2021-07-01 US disclosed
US-10944063-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-03-09 US disclosed
US-10870796-B2 Organic light emitting polymer comprising light-emitting repeat unit in backbone of polymer and device therewith CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2020-12-22 US disclosed
EP-3719099-A1 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2020-10-07 EP disclosed
US-20200176693-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-04 US disclosed
EP-3327100-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2020-05-06 EP disclosed
US-10600975-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-03-24 US disclosed
CN-1143418-A Stable ionomeric photoresist emulsion and process of preparation and use thereof GRACE W R & CO (US) 1997-02-19 CN disclosed
EP-0714391-A1 SUBSTITUTED 2(5H)FURANONE, 2(5H)THIOPHENONE AND 2(5H)PYRROLONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ENDOTHELIN ANTAGONISTS WARNER-LAMBERT COMPANY (US) 1996-06-05 EP disclosed
WO-1995005376-A1 SUBSTITUTED 2(5H)FURANONE, 2(5H)THIOPHENONE AND 2(5H)PYRROLONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ENDOTHELIN ANTAGONISTS WARNER-LAMBERT COMPANY (US) 1995-02-23 WO disclosed
EP-0280434-B1 AROMATIC DISAZO COMPOUND IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-01-22 EP disclosed
US-4908435-A Aromatic disazo compounds having strong infra-red absorption IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-03-13 US disclosed
EP-0280434-A2 Aromatic disazo compound IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-08-31 EP disclosed
US-4652660-A OXIDATION BAYER AKTIENGESELLSCHAFT (DE) 1987-03-24 US disclosed
US-4299966-A Process for the preparation of 4,4',7,7'-tetrachlorthioindigo in pigment form BAYER AKTIENGESELLSCHAFT (DE) 1981-11-10 US disclosed
US-4104180-A HYDROLYZING A METAL ALKOXYALKOXIDE, CARBONATION; DETERGENT ADDITIVES FOR LUBRICANTS EXXON RESEARCH & ENGINEERING CO. (US) 1978-08-01 US disclosed